Persisting post-infection symptoms 2 years after a large waterborne outbreak of Cryptosporidium hominis in northern Sweden

BMC Research Notes
Mikael LiljaJohan Lindh

Abstract

In 2010-2011, a large waterborne outbreak of Cryptosporidium hominis affected the city of Östersund in Sweden. Previous findings had suggested that gastrointestinal symptoms can persist for up to 11 months after the initial infection. Here we investigated whether the parasite could cause sequelae in infected individuals up to 28 months after the outbreak. We compared cases linked to the outbreak and the previous follow-up study with non-cases regarding symptoms present up to 28 months after the initial infection. We investigated whether cases were more likely to report a list of symptoms at follow-up compared to non-cases, calculating odds ratio and 95% confidence interval obtained through logistic regression. A total of 559 individuals (215 cases) were included in the study. Forty-eight percent of the outbreak cases reported symptoms at follow-up. Compared to non-cases, cases were more likely to report watery diarrhea, diarrhea, abdominal pain, fatigue, nausea, headache, or joint stiffness/pain/discomfort at follow-up after adjusting for age and sex. Our findings suggest that gastrointestinal symptoms and joint pain can persist several years after the initial Cryptosporidium infection and should be regarded as a potential caus...Continue Reading

References

Jun 1, 1991·Journal of Clinical Pathology·D P Casemore
May 1, 1989·Archives of Disease in Childhood·R C ShepherdG P Sinha
Jul 25, 1987·British Medical Journal·E M HayM W McKendrick
Jul 1, 1995·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·W R MacKenzieJ P Davis
Sep 10, 2004·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Paul R HunterJohn Goodacre
Aug 25, 2007·Annual Review of Clinical Psychology·Neil SchneidermanScott D Siegel
Feb 3, 2009·Transactions of the Royal Society of Tropical Medicine and Hygiene·K MørchN Langeland
Jun 24, 2009·Experimental Parasitology·Rachel M Chalmers, Angharad P Davies
Oct 30, 2009·The New England Journal of Medicine·Roger I GlassMary K Estes
Aug 11, 2012·Epidemiology and Infection·M InsulanderB Svenungsson
Jan 9, 2013·Clinical Microbiology Reviews·Maha BouzidKevin M Tyler
Mar 25, 2014·Emerging Infectious Diseases·Micael WiderströmJohan Lindh
Oct 27, 2016·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·H HarvalaJ Beser

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Citations

Jul 16, 2019·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·B L CarterR M Chalmers
Jul 9, 2020·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·Jessica ÖgrenAndreas Matussek
Sep 6, 2020·Parasites & Vectors·Bethan L CarterAngharad P Davies
Oct 31, 2020·Microorganisms·Manasi SawantSadia Benamrouz-Vanneste

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