Personal exposure to fine particles (PM2.5 ) and respiratory inflammation of common residents in Hong Kong

Environmental Research
Zhanlan FanKin-Fai Ho

Abstract

Given the lack of research on the personal exposure to fine particles (PM2.5) in Hong Kong, we examined the association between short-term personal exposure to PM2.5 and their constituents and inflammation in exhaled breath in a sample of healthy adult residents. Forty-six participants underwent personal PM2.5 monitoring for averagely 6 days to obtain 276 samples. Fractional exhaled nitric oxide (FeNO), a biomarker of inflammation in exhaled breath, was measured at the end of each 24-h personal monitoring. PM2.5 chemical constituents, including organic carbon, elemental carbon, 16 polycyclic aromatic hydrocarbons (PAHs), and 6 phthalate esters, were speciated from the personal samples collected. A mixed-effects model was used to estimate the association of PM2.5 and their constituents with FeNO. The comparison was also made with parallel analyses using ambient concentrations. Personal exposures to PM2.5 (28.1 ± 23.3 μg/m3) were higher than the ambient levels (13.3 ± 6.4 μg/m3) monitored by stations. The composition profile and personal-to-ambient concentration ratio varied among subjects with different occupations. An interquartile range (IQR) change in personal exposure to PM2.5 was positively associated with 12.8% increase in...Continue Reading

Citations

Nov 18, 2018·The Science of the Total Environment·Xiao-Cui ChenKin-Fai Ho
Apr 4, 2021·International Journal of Environmental Research and Public Health·Xuan ZhangNing Tang
Mar 18, 2021·Environmental Health : a Global Access Science Source·Luyi LiXinbiao Guo
Aug 14, 2020·The Science of the Total Environment·Chun LinMiranda Loh
Dec 7, 2018·Environmental Science & Technology·Courtney RoperRobert L Tanguay

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