Personality neuroscience and psychopathology: should we start with biology and look for neural-level factors?

Personality Neuroscience
Neil McNaughton

Abstract

"Personality is an abstraction used to explain consistency and coherency in an individual's pattern of affects, cognitions, desires and behaviors [ABCDs]" (Revelle, 2007, p. 37). But personality research currently provides more a taxonomy of patterns than theories of fundamental causes. Psychiatric disorders can be viewed as involving extremes of personality but are diagnosed via symptom patterns not biological causes. Such surface-level taxonomic description is necessary for science, but consistent predictive explanation requires causal theory. Personality constructs, and especially their clinical extremes, should predict variation in ABCD patterns, with parsimony requiring the lowest effective causal level of explanation. But, even biologically inspired personality theories currently use an intuitive language-based approach for scale development that lacks biological anchors. I argue that teleonomic "purpose" explains the organisation and outputs of conserved brain emotion systems, where high activation is adaptive in specific situations but is otherwise maladaptive. Simple modulators of whole-system sensitivity evolved because the requisite adaptive level can vary across people and time. Sensitivity to a modulator is an abst...Continue Reading

References

Dec 1, 1991·Psychological Reports·C R CloningerD M Svrakic
Jan 1, 1990·Psychopharmacology·D C BlanchardR J Rodgers
Jul 1, 1990·The British Journal of Psychiatry : the Journal of Mental Science·G AndrewsS Henderson
Apr 1, 1987·Journal of Neurochemistry·J HebebrandP Propping
Jan 1, 1987·Journal of Psychiatric Research·C R Cloninger, S B Gilligan
Aug 1, 1970·Behaviour Research and Therapy·J A Gray
Jul 1, 1981·Psychophysiology·R Schandry
Aug 1, 1995·The American Journal of Psychiatry·C BenkelfatA Evans
Jun 1, 1994·Scientific American·J E LeDoux
Dec 1, 1993·Archives of General Psychiatry·C R CloningerT R Przybeck
Jan 7, 1998·Neuroscience and Biobehavioral Reviews·R J BlanchardD C Blanchard
May 29, 1998·American Journal of Medical Genetics·Z WangR R Crowe
Jun 22, 2002·Pharmacology, Biochemistry, and Behavior·Julia LehmannMoshe Gavish
Apr 1, 1953·Journal of Abnormal Psychology·J A TAYLOR
Jul 1, 1956·Psychological Bulletin·J A TAYLOR
Jul 1, 2004·Neuroscience and Biobehavioral Reviews·Neil McNaughton, Philip J Corr
Mar 16, 2005·Consciousness and Cognition·Jaak Panksepp
Aug 16, 2005·Neuroscience and Biobehavioral Reviews·Jeffrey Burgdorf, Jaak Panksepp
Mar 24, 2006·Progress in Neuro-psychopharmacology & Biological Psychiatry·Jaak Panksepp
Aug 9, 2006·Archives of General Psychiatry·Carlos A ZarateHusseini K Manji
Dec 1, 1948·Journal of Comparative and Physiological Psychology·J S BROWN
Apr 24, 2008·International Journal of Psychophysiology : Official Journal of the International Organization of Psychophysiology·Roger A MooreDave Forrester
Jun 2, 2009·Brain Research Bulletin·Simona GardiniAnnalena Venneri
Mar 9, 2010·NeuroImage·Sarah Durston
Aug 25, 2010·Journal of the American Academy of Child and Adolescent Psychiatry·Benjamin M NealeUNKNOWN Psychiatric GWAS Consortium: ADHD Subgroup
May 28, 2011·American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics·Samuele CorteseJoseph Sergeant
Nov 9, 2011·Proceedings of the National Academy of Sciences of the United States of America·James E Herbert-ReadAshley J W Ward
Mar 1, 2012·Current Biology : CB·Andrew J King, David J T Sumpter
Mar 1, 2012·Neuron·Joseph LeDoux
Jun 27, 2012·International Journal of Psychophysiology : Official Journal of the International Organization of Psychophysiology·Roger A MoorePhilip J Corr
Oct 9, 2012·Neuroscience and Biobehavioral Reviews·Philip J Corr, Neil McNaughton
Dec 25, 2012·Journal of Affective Disorders·Neil McNaughtonPaul Glue
Apr 13, 2013·Visual Neuroscience·Dan-E Nilsson
Jun 21, 2013·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Carolyn I RodriguezHelen B Simpson
May 21, 2015·JAMA Psychiatry·UNKNOWN Genetics of Personality ConsortiumDorret I Boomsma
Oct 16, 2016·Development and Psychopathology·Neil McNaughton, Philip J Corr

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