Personalized Ventilation to Multiple Patients Using a Single Ventilator: Description and Proof of Concept

Critical Care Explorations
Jay S HanArthur S Slutsky

Abstract

To design and test a ventilator circuit that can be used for ventilation of two or more patients with a single ventilator, while allowing individualization of tidal volume, fractional concentration of oxygen, and positive end-expiratory pressure to each patient, irrespective of the other patient's respiratory system mechanics. Description and proof of concept studies. Respiratory therapy laboratory. Ventilation of mechanical test lungs. Following a previously advocated design, we used components readily available in our hospital to assemble two "bag-in-a-box" breathing circuits. Each patient circuit consisted of a flexible bag in a rigid container connected via one-way valve to a test lung, along with an inline positive end-expiratory pressure valve, connected to the ventilator's expiratory limb. Compressed gas fills the bags during "patient" exhalation. During inspiration, gas from the ventilator, in pressure control mode, enters the containers and displaces gas from the bags to the test lungs. We varied tidal volume, "respiratory system" compliance, and positive end-expiratory pressure in one lung and observed the effect on the tidal volume of the other. We were able to obtain different tidal volume, dynamic driving pressure,...Continue Reading

References

Aug 4, 2006·Academic Emergency Medicine : Official Journal of the Society for Academic Emergency Medicine·Greg Neyman, Charlene Babcock Irvin
Oct 19, 2011·Respiratory Care·Richard D BransonJay A Johannigman

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Citations

Jul 2, 2020·American Journal of Respiratory and Critical Care Medicine·Jordi ManceboLaurent Brochard
Jan 20, 2021·PloS One·Claude GuérinLaurent Argaud

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