Personalizing care for nonalcoholic fatty liver disease patients: what are the research priorities?

Personalized Medicine
Silvia Sookoian, Carlos J Pirola

Abstract

Nonalcoholic fatty liver disease (NAFLD) is a common chronic liver disease whose prevalence has reached global epidemic proportions, not only in adults but also in children. From a clinical point of view, NAFLD stems a myriad of challenges to physicians, researchers and patients. In this study, we revise the current knowledge and recent insights on NAFLD pathogenesis and diagnosis in the context of a personalized perspective with special focus on the following issues: noninvasive biomarkers for the evaluation of disease severity and progression, lifestyle-related patients' recommendations, risk prediction of disease by genetic testing, management of NAFLD-associated comorbidities and patient-oriented therapeutic intervention strategies.

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Citations

Oct 14, 2018·Pharmaceuticals·Ludovico AbenavoliNazarii Kobyliak
Feb 8, 2021·Computers in Biology and Medicine·Athina I Amanatidou, George V Dedoussis

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Methods Mentioned

BETA
biopsy

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