Persons with essential tremor can adapt to new walking patterns

Journal of Neurophysiology
Jaimie A RoperChris J Hass

Abstract

Essential tremor (ET) is a common movement disorder that causes motor deficits similar to those seen in cerebellar disorders. These include kinetic tremor, gait ataxia, and impaired motor adaptation. Previous studies of motor adaptation in ET have focused on reaching while the effects of ET on gait adaptation are currently unknown. The purpose of this study was to contrast locomotor adaptation in persons with and without ET. We hypothesized that persons with ET would show impaired gait adaptation. In a cross-sectional study, persons with ET (n = 14) and healthy matched controls (n = 12) walked on a split-belt treadmill. Participants walked with the belts moving at a 2:1 ratio, followed by overground walking to test transfer, followed by a readaptation period and finally a deadaptation period. Step length asymmetry was measured to assess the rate of adaptation, amount of transfer, and rates of readaptation and deadaptation. Spatial, temporal, and velocity contributions to step length asymmetry were analyzed during adaptation. There were no group by condition interactions in step length asymmetry or contributions to step length asymmetry. Regardless of condition, persons with ET walked slower and exhibited lower temporal (P < 0.0...Continue Reading

References

Dec 17, 1997·Movement Disorders : Official Journal of the Movement Disorder Society·J P HubbleW C Koller
Oct 24, 2001·Brain : a Journal of Neurology·H StolzeG Deuschl
Jun 17, 2005·Journal of Neurophysiology·Darcy S ReismanAmy J Bastian
Oct 8, 2005·Movement Disorders : Official Journal of the Movement Disorder Society·Peter TrillenbergChristoph Helmchen
Dec 17, 2005·Cerebral Cortex·Haiyin ChenReza Shadmehr
May 16, 2006·Movement Disorders : Official Journal of the Movement Disorder Society·Zsuzsanna FarkasAnita Kamondi
Sep 8, 2006·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Susanne M Morton, Amy J Bastian
Apr 5, 2007·Brain : a Journal of Neurology·Darcy S ReismanAmy J Bastian
May 1, 2007·Brain : a Journal of Neurology·Martin KronenbuergerDagmar Timmann
Nov 8, 2008·Current Opinion in Neurology·Amy J Bastian
Nov 14, 2008·Movement Disorders : Official Journal of the Movement Disorder Society·Gammon M EarhartJoel S Perlmutter
Mar 25, 2009·Neurorehabilitation and Neural Repair·Darcy S ReismanAmy J Bastian
Nov 17, 2009·The European Journal of Neuroscience·Laura AvanzinoGiovanni Abbruzzese
Mar 31, 2011·Journal of Neuroimaging : Official Journal of the American Society of Neuroimaging·Bhavani Shankara BagepallyPramod Kumar Pal
Jun 4, 2013·Gait & Posture·Kristina M FernandezChris J Hass
Aug 7, 2013·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Ryan T RoemmichChris J Hass
Sep 10, 2013·Journal of Biomechanics·Ryan T RoemmichChris J Hass
Sep 14, 2013·Brain : a Journal of Neurology·Rachel BabijElan D Louis
Nov 23, 2013·Parkinsonism & Related Disorders·Elan D Louis
Jan 31, 2014·Journal of Neurophysiology·M J MaclellanF Lacquaniti
Nov 5, 2014·Brain : a Journal of Neurology·Elan D LouisPhyllis L Faust
Jan 16, 2015·Neurorehabilitation and Neural Repair·James M FinleyGelsy Torres-Oviedo
Jun 28, 2015·Brain : a Journal of Neurology·Cécile GalleaSabine Meunier
Jul 24, 2015·Journal of Neurophysiology·Wouter HoogkamerJacques Duysens
Oct 27, 2015·The Cerebellum·Juan Marin-Lahoz, Alexandre Gironell
Nov 2, 2015·The Cerebellum·Julián Benito-León, Andrés Labiano-Fontcuberta
Feb 20, 2016·Orthopaedic Journal of Sports Medicine·Jaimie A RoperChris J Hass
Apr 12, 2016·Movement Disorders : Official Journal of the Movement Disorder Society·Ritsuko HanajimaYoshikazu Ugawa
Aug 26, 2017·The Cerebellum·Matthew A StattonAmy J Bastian
Oct 21, 2017·Tremor and Other Hyperkinetic Movements·Abhishek LenkaElan D Louis
Dec 2, 2017·Movement Disorders : Official Journal of the Movement Disorder Society·Kailash P BhatiaUNKNOWN Tremor Task Force of the International Parkinson and Movement Disorder Society
Apr 17, 2018·Brain : a Journal of Neurology·Constantin TuleascaDimitri Van De Ville

❮ Previous
Next ❯

Citations

Oct 31, 2020·Scientific Reports·Christine N SongRyan T Roemmich

❮ Previous
Next ❯

Software Mentioned

SPSS
BASELINE
EARLY

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.