Persons with schizophrenia migrate towards urban areas due to the development of their disorder or its prodromata

Schizophrenia Research
Carsten B Pedersen

Abstract

Many studies have identified urban-rural differences in the occurrence of schizophrenia. Though unknown, the underlying causes responsible for these differences have been hypothesized to include urban-rural differences in toxic exposures, diet, infections, stress, or an artifact due to selective migration. Freeman hypothesized that persons with schizophrenia migrate towards larger cities due to development of their disorder or its prodromata. Based on this, the reason for the high frequency of schizophrenia in urban areas is not that those affected have lived in environmentally unfavorable areas, but that people with schizophrenia selectively migrate towards urban areas due to disease onset. No population-based studies accessed the extent and potential impact of this artifact of selective migration. Utilizing a population-based sample of the Danish population, it was investigated if persons with schizophrenia more often migrated towards larger cities due to disease onset. The impact of selective migration on the urban-rural differences was quantified comparing a prospective and a retrospective study. Compared to healthy controls, persons with schizophrenia spectrum disorder migrate to a higher degree of urbanization due to dise...Continue Reading

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Citations

Apr 14, 2016·Schizophrenia Research·Theresa WimberleyChristiane Gasse
Feb 26, 2019·Proceedings of the National Academy of Sciences of the United States of America·Kristine EngemannJens-Christian Svenning
Aug 8, 2019·Early Intervention in Psychiatry·Lilith Abrahamyan EmpsonPhilippe Conus
Dec 14, 2018·Nature Communications·Chun Chieh FanCarsten Bøcker Pedersen
May 15, 2021·The Australian and New Zealand Journal of Psychiatry·Oleguer Plana-RipollVera A Morgan

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