Perspective: Human immunodeficiency virus infection in children

American Journal of Human Biology : the Official Journal of the Human Biology Council
Leon G Epstein

Abstract

Epidemiologic studies indicate that the number of women and children with human immunodeficiency virus (HIV) infection will continue to increase in the next decade. The impact of this aspect of the AIDS pandemic, including increased infant mortality, will be greatest in developing nations. The biologic properties of HIV, a lentivirus, complicate the strategies to alter the course of the pandemic. A long asymptomatic interval between initial infection and the onset of clinical disease, the ability of HIV to evade immune clearance, and the propensity for rapid mutation and selection of viral variants all favor survival of the virus over the host.

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Citations

Jan 1, 1990·American Journal of Human Biology : the Official Journal of the Human Biology Council·Janet W McGrath
Jul 1, 1993·Pediatric Annals·J A Church
Nov 3, 1998·Pediatric Annals·G B ZuckermanE E Conway
Apr 1, 1993·Journal of Psychoactive Drugs·G OepenR Boshes

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