Perspectives in fatal epidemics

Infectious Disease Clinics of North America
J C ButlerS M Ostroff

Abstract

This article discusses four epidemics of fatal infectious diseases: a 1993 cluster of deaths among previously healthy persons in the southwestern United States that led to the identification of a new clinical syndrome, hantavirus pulmonary syndrome; the first epidemic of Ebola hemorrhagic fever identified in nearly two decades occurring in 1995 in Zaire, which resulted in 317 cases with a mortality rate of 77%; an outbreak of Legionnaires' disease among cruise ship passengers in 1994; and a 1989 cluster of illnesses among nonhuman primates in Reston, Virginia leading to the identification of a new strain of Ebola virus. In each outbreak, the public health emergency was recognized and reported by alert clinicians, and the control of disease was facilitated through rapid, coordinated responses involving multiple agencies. Such collaboration between clinical and public health entities and among various agencies will be increasingly needed as surveillance and diagnostic capabilities for emerging and reemerging infectious diseases are enhanced around the world.

References

Sep 1, 1995·The Journal of Infectious Diseases·L SimonsenC J Peters
Sep 16, 1995·Lancet·J W FramptonC R Nichols
Jul 22, 1994·MMWR. Morbidity and Mortality Weekly Report·UNKNOWN Centers for Disease Control and Prevention (CDC)
Jan 17, 1996·JAMA : the Journal of the American Medical Association·R W PinnerR L Berkelman
May 1, 1996·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·C R VitekC J Peters
Feb 1, 1996·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·D W KellerR F Breiman

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Citations

Jun 1, 2009·Journal of Vector Ecology : Journal of the Society for Vector Ecology·Douglas G GoodinColleen B Jonsson

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