PMID: 3433664Dec 1, 1987

Perspectives in mucosal immunity: a ruminant model

Veterinary Immunology and Immunopathology
A J Husband

Abstract

All mammalian species have developed specialized defence mechanisms at the interface between mucosal surfaces and the environment and this system operates independently of the systemic immune system. Attachment of organisms to the mucosal epithelium is a primary prerequisite for infection and is an important virulence determinant for pathogens of these sites. The mucosal immune defences are thus characterized by production of IgA antibodies, the principal mode of action of which is to inhibit the adherence of pathogens to the mucosal epithelium. This introduction to the symposium on mucosal immunity will attempt to underline the role of local immunity in the intestine in providing local defence at that site, in addition to providing cellular molecular effectors for other mucosal sites.

References

Apr 1, 1977·The Journal of Experimental Medicine·M McWilliamsM E Lamm
Nov 1, 1977·The Journal of Experimental Medicine·M E RouxM E Lamm
Jun 1, 1975·The Australian Journal of Experimental Biology and Medical Science·J W QuinA K Lascelles
Feb 1, 1974·The Australian Journal of Experimental Biology and Medical Science·K J BehA K Lascelles
Aug 1, 1974·The Australian Journal of Experimental Biology and Medical Science·A W CrippsA K Lascelles

Citations

Aug 11, 2010·Tropical Animal Health and Production·Ina-Salwany Mohd YasinEffendy Abd Wahid Mohd
Apr 1, 1989·Journal of Neuroimmunology·P K Coyle
Feb 14, 1998·Veterinary Parasitology·J Vercruysse, E Claerebout
Dec 1, 1995·Avian Pathology : Journal of the W.V.P.A·W I MuirA J Husband
Apr 1, 1994·Zentralblatt für Veterinärmedizin. Reihe B. Journal of veterinary medicine. Series B·E M LieblerT Landsverk
Oct 1, 1992·Immunology and Cell Biology·V L CliftonD J Kay

Related Concepts

Bacterial Adhesion
Cell Adhesion
IgA2
Structure of Intestinal Gland
Lymph
Udder
Muscularis Mucosae
Respiratory Tract Structure
Oreamnos americanus

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