Perspectives of nuclear diagnostic imaging in diabetic cardiomyopathy

Nutrition, Metabolism, and Cardiovascular Diseases : NMCD
F C SassoL Mansi

Abstract

Diabetic cardiomyopathy is a ventricular dysfunction in the absence of coronary artery disease, valvular or hypertensive heart disease. The mechanisms underlying diabetic cardiomyopathy may involve metabolic disturbances, myocardial fibrosis, small vessel disease, microcirculation abnormalities, cardiac autonomic neuropathy and insulin resistance. Diagnostic problems emerge because no specific disease pattern characterizes the disease and because there may be coexistence in diabetes of coronary artery disease and hypertension as independent but compounding causes of biochemical, anatomical and functional alterations impairing cardiac function. In this paper we will review the role of nuclear imaging today, concentrating on the diagnostic capabilities of radionuclide ventriculography, to study the effect of insulin resistance and, more extensively, gated-single photon emission computed tomography with Tc-99m labelled agents. A broad analysis will be dedicated to: 1) positron emission tomography using perfusion agents, with the potential to quantify resting and stress blood flow and coronary flow reserve; 2) radionuclide procedures evaluating aerobic and anaerobic cardiac metabolism; and 3) cardiac neurotransmission imaging, stud...Continue Reading

References

Dec 1, 1992·Cardiovascular Research·G D LopaschukT Itoi
Feb 14, 1998·Journal of the American College of Cardiology·R ScognamiglioS Dalla Volta
Jul 21, 1998·Journal of the American College of Cardiology·S Iskander, A E Iskandrian
Aug 25, 1999·Journal of Hypertension·G Grassi, M Esler
Jan 11, 2000·Circulation Research·A FrustaciP Anversa
Jul 5, 2001·Diabetic Medicine : a Journal of the British Diabetic Association·H S ChenL T Ho
Jul 14, 2001·Journal of the American College of Cardiology·N TakahashiT Sakata
Feb 15, 2002·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Amar D Patel, Ami E Iskandrian
Apr 4, 2003·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Rishi AroraMark I Travin
May 6, 2004·Annals of Internal Medicine·Manuel J QuiñonesWilla A Hsueh
Jan 5, 2005·Journal of the American College of Cardiology·Marcelo F Di Carli, Rory Hachamovitch
Apr 23, 2005·European Heart Journal·Ferdinando C SassoDomenico Cozzolino
Feb 7, 2006·Journal of the American College of Cardiology·Pilar HerreroRobert J Gropler
Oct 19, 2007·Diabetes, Obesity & Metabolism·B A BrooksS M Twigg
Apr 12, 2008·Cardiovascular Pathology : the Official Journal of the Society for Cardiovascular Pathology·Georgios F DiakakisPanos E Vardas
Apr 16, 2009·JAMA : the Journal of the American Medical Association·Lawrence H YoungUNKNOWN DIAD Investigators

❮ Previous
Next ❯

Citations

Apr 25, 2012·Current Diabetes Reports·Maggie N Tillquist, Thomas M Maddox
Feb 1, 2012·Journal of Cognitive Neuroscience·Timothy R Koscik, Daniel Tranel
May 10, 2013·Orthopaedic Surgery·Simerjit Singh Madan, Dinker R Pai
Feb 25, 2017·Cardiovascular Diabetology·A Lorenzo-AlmorósÓ Lorenzo
Jun 26, 2021·World Journal of Diabetes·Marko KumricJosko Bozic
Jul 3, 2021·International Journal of Molecular Sciences·Petra Grubić RotkvićLuka Rotkvić
Feb 11, 2011·Current Opinion in Cardiology
Aug 13, 2011·Current Opinion in Cardiology

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cardiovascular Inflammation

Inflammation plays a significant role in the development of cardiovascular diseases, an understanding of these endogenous processes is critical for evaluating the risks and potential treatment strategies. Discover the latest research on cardiovascular inflammation here.

Cardiovascular Disease Pathophysiology

Cardiovascular disease involves several different processes that contribute to the pathological mechanism, including hyperglycemia, inflammation, atherosclerosis, hypertension and more. Vasculature stability plays a critical role in the development of the disease. Discover the latest research on cardiovascular disease pathophysiology here.

CV Disorders & Type 2 Diabetes

This feed focuses on the association of cardiovascular diseases in patients with type 2 diabetes.

Atrial Fibrillation

Atrial fibrillation is a common arrhythmia that is associated with substantial morbidity and mortality, particularly due to stroke and thromboembolism. Here is the latest research.

Arrhythmia

Arrhythmias are abnormalities in heart rhythms, which can be either too fast or too slow. They can result from abnormalities of the initiation of an impulse or impulse conduction or a combination of both. Here is the latest research on arrhythmias.

Cardiomyopathy

Cardiomyopathy is a disease of the heart muscle, that can lead to muscular or electrical dysfunction of the heart. It is often an irreversible disease that is associated with a poor prognosis. There are different causes and classifications of cardiomyopathies. Here are the latest discoveries pertaining to this disease.

Cardiovascular Diseases: Risk Factors

Cardiovascular disease is a significant health concern. Risk factors include hypertension, obesity, dyslipidemia and smoking. Women who are postmenopausal are at an increased risk of heart disease. Here is the latest research for risk factors of cardiovascular disease.