Perspectives of South African youth in the development of an implant for HIV prevention

Journal of the International AIDS Society
Emily A KrogstadAriane van der Straten

Abstract

Implants are a new dosage form in development for HIV pre-exposure prophylaxis (PrEP) with potential for high adherence given that they are provider-administered and are intended for long-acting protection. Integrating end-user preference into early stage product development may further overcome challenges with future product uptake and adherence. Hence, we sought to optimize the design of a PrEP implant in early-stage development by gathering opinions about implant attributes from potential end-users in South Africa. We conducted 14 focus group discussions (FGDs) with young women and men aged 18 to 24 in Cape Town and Soshanguve, South Africa, inviting participants into discussion as co-designers. FGDs were homogenous by gender and previous implant experience. During FGDs, we showed prototype devices and followed a semi-structured guide with questions on history of contraceptive implant use, preferences for physical characteristics of an implant, implant biodegradability, insertion process, participant-driven ideas for implant design, and social adoption considerations. FGDs were facilitated in English, isiXhosa, Tswana, isiZulu, or Tsonga, audio-recorded, transcribed into English, and qualitatively coded and analysed. In this...Continue Reading

References

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Citations

Apr 2, 2019·AIDS Patient Care and STDs·Emily A KrogstadAriane van der Straten
Mar 14, 2019·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Elizabeth T MontgomeryAlexandra M Minnis
Mar 29, 2020·Culture, Health & Sexuality·Emily A KrogstadLinda-Gail Bekker
Jan 27, 2020·Contraception·Emily A KrogstadAriane van der Straten
Feb 27, 2021·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Elizabeth T MontgomeryAlexandra M Minnis
Jan 1, 2022·AIDS Research and Human Retroviruses·Imogen HawleyAriane van der Straten

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Methods Mentioned

BETA
contraception

Software Mentioned

Soshanguve
Dedoose

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