Pertubation with lidocaine--a non-hormonal, long-term treatment of dysmenorrhea due to endometriosis

Sexual & Reproductive Healthcare : Official Journal of the Swedish Association of Midwives
Greta EdelstamJack Spira

Abstract

The major symptoms of endometriosis are dysmenorrhea and infertility. Pertubations with lidocaine have been shown to reduce dysmenorrhea and have an enhancing effect on fertility. Different concentrations of lidocaine were evaluated in a randomized, double-blind study of pre-ovulatory pertubations with lidocaine solutions in women with dysmenorrhea. The patients had laparoscopically diagnosed endometriosis and normal fallopian tubes. Ninety pertubations were carried out without complications on 26 patients during up to six cycles. The effect was evaluated by means of questionnaires where a clinically significant reduction of dysmenorrhea was reported. Pertubation with lidocaine can be a non-hormonal treatment option for dysmenorrhea.

References

Jan 31, 2002·Upsala Journal of Medical Sciences·G A EdelstamC W Salamon
Apr 6, 2006·The Journal of Obstetrics and Gynaecology Research·Charalambos SiristatidisEmmanuel Salamalekis
Oct 20, 2009·Journal of Minimally Invasive Gynecology·Fred M Howard

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Citations

Aug 8, 2013·Drugs in R&D·Karin WickströmGreta Edelstam
Jun 14, 2015·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·Tarek Shokeir, Sherif Mousa
Jul 1, 2014·Current Opinion in Obstetrics & Gynecology·Lieven Platteeuw, Thomas D'Hooghe

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