Perturbation-evoked cortical activity reflects both the context and consequence of postural instability

Neuroscience
G MochizukiWilliam E McIlroy

Abstract

The cerebral cortex may play a role in the control of compensatory balance reactions by optimizing these responses to suit the task conditions and/or to stimulus (i.e. perturbation) characteristics. These possible contributions appear to be reflected by pre-perturbation and post-perturbation cortical activity. While studies have explored the characteristics and possible meaning of these different events (pre- vs. post-) there is little insight into the possible association between them. The purpose of this study was to explore whether pre- and post-perturbation cortical events are associated or whether they reflect different control processes linked to the control of balance. Twelve participants were presented temporally-predictable postural perturbations under four test conditions. The Block/Random tasks were designed to assess modifiability in CNS gain prior to instability, while the Unconstrained/Constrained tasks assessed responsiveness to the magnitude of instability. Perturbations were evoked by releasing a cable which held the participant in a forward lean position. The magnitude of pre-perturbation cortical activity scaled to perturbation amplitude when the magnitude of the perturbation was predictable [F(3,11)=2.906, P...Continue Reading

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Citations

May 18, 2011·Experimental Brain Research·David A E BoltonW Richard Staines
Aug 18, 2012·BMC Neuroscience·David A E BoltonWilliam E McIlroy
Jun 28, 2014·Neuroscience Letters·Jessy Parokaran VargheseWilliam E McIlroy
Jan 19, 2016·Frontiers in Human Neuroscience·Thorben HülsdünkerHeiko K Strüder
Sep 1, 2015·Neuroscience and Biobehavioral Reviews·D A E Bolton
May 15, 2016·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Alison Schinkel-IvyAvril Mansfield
Apr 15, 2014·Gait & Posture·Alexander D WrightAndrew C Laing
Sep 11, 2014·Journal of Motor Behavior·Cameron D HassallOlave E Krigolson
Mar 18, 2017·Experimental Brain Research·Kwang Leng GohTele Tan
Jun 25, 2017·Gait & Posture·Nametala Maia AzziLuis Augusto Teixeira
Nov 24, 2017·Journal of Autism and Developmental Disorders·Kwang Leng GohTele Tan
Dec 6, 2018·Journal of Neurophysiology·Aiden M PayneLena H Ting
May 13, 2018·Experimental Brain Research·Rahul GoelPranav J Parikh
Nov 28, 2019·The European Journal of Neuroscience·Luis Augusto TeixeiraDaniel Boari Coelho
May 24, 2014·Reviews in the Neurosciences·Kathryn M SibleyWilliam E McIlroy
Aug 25, 2020·Neurorehabilitation and Neural Repair·Shu-Han YuCheng-Ya Huang
Sep 16, 2020·The European Journal of Neuroscience·T Solis-EscalanteV Weerdesteyn
Sep 14, 2012·Journal of Neurophysiology·A D CampbellM G Carpenter
Mar 10, 2016·Experimental Brain Research·David CioncoloniRiccardo Mazzocchio
Nov 15, 2018·Frontiers in Neurology·Christopher J Dakin, David A E Bolton

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