Abstract
Pertussis is a contagious bacterial disease causing substantial health burden. Pertussis-related morbidity and mortality are highest in young infants. We investigated risk markers for pertussis and vaccination status in infants. Reported pertussis cases under one year old during 1998-2011 in the Jerusalem district were matched to controls by birthdate and residence. Data sources included epidemiological investigations, health records and vaccination records (number and dates of DTP\DTaP doses scheduled at 2, 4, 6 months). Vaccine effectiveness was calculated by number of vaccine doses stratified by age group. Timeliness of vaccine doses was also evaluated. The study population included 1268 infants under 1 year: 317 pertussis cases and 951 age-matched controls (mean age 3.95±3, median 2.9 months). Low birthweight (<2500g, 12.3% in cases vs. 6.3% in controls) and high birth order (4th and above) were found to be independent risk markers. Male gender and low socio-economic status were more frequent among cases. Some 40% of the cases (127/317) were hospitalized, most of them (111/127, 87.4%) were under 4 months (mean age 2.42±2.05, median 1.8 months). The distribution of the number of pertussis vaccine doses 0, 1, 2 and 3 differed...Continue Reading
References
May 1, 1996·The Journal of Pediatrics·D L Langkamp, J P Davis
May 10, 2002·European Journal of Pediatrics·Siegfried LugauerKlemens Stehr
Dec 7, 2002·The Lancet Infectious Diseases·C H Wirsing von KönigN Guiso
Apr 19, 2003·BMJ : British Medical Journal·Cameron C GrantRosalie Menzies
Mar 12, 2004·The Pediatric Infectious Disease Journal·Elizabeth ElliottGeoff Knight
Aug 3, 2005·Pediatrics·Kristine M BisgardUNKNOWN Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA. kbisgard@cdc.gov
Sep 9, 2005·The Pediatric Infectious Disease Journal·Lucia Pastore CelentanoUNKNOWN EUVAC-NET Group
Feb 7, 2007·Vaccine·Kevin D ForsythStanley Plotkin
Aug 21, 2007·Vaccine·Valérie BriandDaniel Lévy-Bruhl
Jul 8, 2008·Vaccine·Anna GiammancoIldiko Karacs
Feb 12, 2009·The Pediatric Infectious Disease Journal·Dana L HaberlingTrudy V Murphy
Apr 28, 2009·Current Opinion in Infectious Diseases·Peter McIntyre, Nicholas Wood
May 15, 2010·Lancet·Robert E BlackUNKNOWN Child Health Epidemiology Reference Group of WHO and UNICEF
Nov 9, 2010·Vaccine·Chen Stein-ZamirGary Zentner
Nov 19, 2011·Vaccine·Lennart NilssonLennart Gustafsson
Jan 21, 2012·Emerging Infectious Diseases·Helen CampbellElizabeth Miller
Jun 20, 2012·Vaccine·Angela BechiniPaolo Bonanni
Aug 17, 2012·The New England Journal of Medicine·James D Cherry
Oct 10, 2012·New South Wales Public Health Bulletin
Jan 11, 2013·Human Vaccines & Immunotherapeutics·Inma Crespo FernándezUNKNOWN Pertussis Surveillance Group of Catalonia
Mar 28, 2013·BMC Infectious Diseases·Elena ChiappiniMaurizio de Martino
May 24, 2013·Archives of Disease in Childhood·Gayatri Amirthalingam
Sep 11, 2013·JAMA Pediatrics·Jason M GlanzEric S Weintraub
Oct 23, 2013·Pediatrics·Katherine A AugerMatthew M Davis
Mar 15, 2014·The Journal of Infectious Diseases·Thomas A Clark
Mar 15, 2014·The Journal of Infectious Diseases·Drusilla L BurnsNancy E Messionnier
Jul 11, 2014·Chest·Joshua D Hartzell, Jason M Blaylock
Aug 22, 2014·Expert Review of Vaccines·Carl-Heinz Wirsing von König
Sep 1, 2014·Vaccine·Bahaa Abu RayaEllen Bamberger
Citations
May 26, 2016·PloS One·Hanqing HeJinren Pan
Jul 12, 2017·Human Vaccines & Immunotherapeutics·Chen Stein-Zamir, Avi Israeli
Feb 15, 2019·The Pediatric Infectious Disease Journal·Chen Stein-ZamirHanna Shoob
Jan 12, 2017·Journal of the Pediatric Infectious Diseases Society·Michelle M HughesJoanne Katz
Jul 19, 2019·Vaccines·Hannah ChisholmHelen Petousis-Harris
Oct 31, 2019·BMC Infectious Diseases·Nicoline A T van der MaasHester E de Melker
Apr 14, 2017·The Pediatric Infectious Disease Journal·Øystein Rolandsen RiiseJann Storsæter
Feb 6, 2019·BMC Public Health·Sílvia BruguerasUNKNOWN Barcelona Pertussis Working Group
May 29, 2018·Journal of Public Health Policy·Emilia AnisEsther Marva
Dec 17, 2020·Human Vaccines & Immunotherapeutics·Dov Bary-Weisberg, Chen Stein-Zamir
Jan 15, 2019·Archives de pédiatrie : organe officiel de la Sociéte française de pédiatrie·A RybakC Levy
May 4, 2021·Vaccine·Krista WilkinsonSalaheddin M Mahmud
Jun 24, 2016·Microbiology Spectrum·Delma J Nieves, Ulrich Heininger
Nov 5, 2019·International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases·Federica BrosioGiovanni Gabutti