PMID: 9188218May 29, 1997Paper

Pertussis notifications in Australia, 1991 to 1997

Communicable Diseases Intelligence
Ross AndrewsC Roberts

Abstract

Although pertussis is a vaccine-preventable disease, it has been epidemic in Australia since 1993 and recently claimed the lives of four children under three months of age. We reviewed national notifications of pertussis from 1991 to 1997 and found notification rates ranged from 2.0 per 100,000 population in 1991 to a peak of 30.5 per 100,000 population in 1994 despite pertussis vaccination coverage approaching 90% for the three-dose primary course. We found that notification rates were highest in infants (< 1 year of age) and school aged children (5-14 years of age). Although there was a resurgence of pertussis in 1996, age-specific notification rates decreased for children aged 1-7 years and it appears that the diphtheria-tetanus-pertussis (DTP) booster introduced as a fifth dose at 4-5 years may be having an effect. We raise the possibility that the current whole cell pertussis vaccine may be providing only short-term immunity and that our results may reflect low or inadequate vaccine coverage among both the population at large and the individual cases. We identify gaps in the national surveillance system which require attention including under-reporting and the need for information on vaccination status of notified cases; m...Continue Reading

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

The Pediatric Infectious Disease Journal
Siranda Torvaldsen, Peter B McIntyre
Developments in Biological Standardization
B Ivanoff, S E Robertson
Przegla̧d epidemiologiczny
J Tomaszunas-Błaszczyk
© 2021 Meta ULC. All rights reserved