Pesticide exposures and fetal death: a review of the epidemiologic literature

Critical Reviews in Toxicology
Tye E Arbuckle, L E Sever

Abstract

Despite considerable concern regarding the effects on reproductive outcome of exposures to pesticides, convincing evidence for the developmental toxicity of occupational and environmental pesticide exposure in humans is lacking. In this comprehensive review of the English language epidemiologic literature, we summarize studies that have examined potential associations between fetal deaths (both spontaneous abortions and stillbirths) and specific pesticides, as well as maternal and paternal employment in occupations with potential for exposure. While many of the epidemiologic studies to date suffer from methodologic problems, the data are suggestive of increased risks of fetal deaths associated with pesticides in general and maternal employment in the agricultural industry. There is a clear need for epidemiologic research that focuses on specific pesticide products or chemical families, with improved exposure assessment. The potential role of solvents in developmental toxicity associated with pesticide use by both males and females should also be considered.

References

Mar 8, 1979·Nature·C Cookson
Jan 1, 1992·American Journal of Industrial Medicine·J ZhangD J Lee
Mar 1, 1992·Early Human Development·J Zhang, W W Cai
Feb 1, 1991·Scandinavian Journal of Work, Environment & Health·L Goulet, G Thériault
Jan 1, 1990·Journal of Clinical Epidemiology·S S Coughlin
Jan 1, 1990·American Journal of Industrial Medicine·M L LindbohmK Hemminki
Jul 1, 1990·American Journal of Epidemiology·M B SchenkerP Wiggins
Aug 1, 1990·Scandinavian Journal of Work, Environment & Health·M RestrepoX Nguyen-Dinh
Oct 1, 1990·American Journal of Public Health·A Aschengrau, R R Monson
Jul 1, 1990·Archives of Environmental Health·L R GoldmanK W Kizer
May 1, 1989·British Journal of Industrial Medicine·A D McDonaldD Robert
Jul 1, 1989·Journal of Occupational Medicine. : Official Publication of the Industrial Medical Association·A Aschengrau, R R Monson
Jun 1, 1989·Scandinavian Journal of Work, Environment & Health·G AhlborgS Bárány
Oct 1, 1989·Scandinavian Journal of Work, Environment & Health·H TaskinenK Hemminki
Jan 1, 1985·Teratogenesis, Carcinogenesis, and Mutagenesis·J D Constable, M C Hatch
May 1, 1988·The Journal of Infection·J P DickD V Hamilton
Mar 1, 1988·British Journal of Industrial Medicine·A D McDonaldD Robert
Jul 1, 1988·Human Toxicology·L KarallieddeA Ariaratnam
Dec 1, 1987·Forensic Science International : Synergy·H Tsoukali-Papadopoulou, S Njau
Feb 1, 1986·Scandinavian Journal of Work, Environment & Health·D A SchwartzR M Heifetz
Aug 1, 1987·British Journal of Industrial Medicine·A D McDonaldD Robert
Jan 1, 1986·International Journal of Health Services : Planning, Administration, Evaluation·T D Sterling, A Arundel
Feb 23, 1985·British Medical Journal·F W JohnsonK M Hadley
Jul 20, 1968·British Medical Journal·D C AbbottJ O Tatton
Nov 1, 1969·Archives of Environmental Health·A CurleyR D Kimbrough
Dec 15, 1970·American Journal of Obstetrics and Gynecology·J A O'LearyM Feldman
Sep 21, 1968·British Medical Journal·J J FennellyR T Carroll
May 11, 1984·JAMA : the Journal of the American Medical Association·R R Suskind, V S Hertzberg
Sep 1, 1984·American Journal of Epidemiology·M L LindbohmP Kyyrönen
Jan 1, 1984·Archives of Environmental Health·C C RoanD P Morgan
Mar 1, 1984·Archives of Environmental Health·J R GoldsmithR Israeli
Sep 1, 1982·Journal of Clinical Pathology·A FletcherI C Talbot
May 1, 1982·American Journal of Epidemiology·J C TownsendR R Cook
Jul 1, 1982·Archives of Environmental Health·A H SmithC J Chapman
Nov 1, 1982·Postgraduate Medical Journal·F A Musson, C A Porter

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Citations

Jul 1, 2010·Journal of Exposure Science & Environmental Epidemiology·Xiangmei May WuIrva Hertz-Picciotto
Apr 17, 2009·International Journal of Environmental Health Research·James Gomes, Owen L Lloyd
Nov 9, 2006·Journal of Toxicology and Environmental Health. Part B, Critical Reviews·L RitterMark Raizenne
Dec 13, 2007·Journal of Toxicology and Environmental Health. Part B, Critical Reviews·Donald T WigleDaniel Krewski
Dec 13, 2007·Journal of Toxicology and Environmental Health. Part B, Critical Reviews·M WeselakW Foster
May 13, 2008·Journal of Toxicology and Environmental Health. Part B, Critical Reviews·Donald T WigleDaniel Krewski
Oct 10, 2009·BMC International Health and Human Rights·Alexis J Handal, Sioban D Harlow
Jun 2, 2006·Reproductive Biology and Endocrinology : RB&E·Reini W BretveldNel Roeleveld
Apr 4, 2002·Environmental Health Perspectives·Thomas A ArcuryGregory B Russell
May 4, 2004·Environmental Health Perspectives·Anne R GreenleeRichard L Berg
May 24, 2007·Environmental Health Perspectives·Beth A MuellerKay M Tomashek
Mar 28, 2008·Journal of Toxicology and Environmental Health. Part B, Critical Reviews·Mandy WeselakDaniel Krewski
Jun 15, 2013·Journal de gynécologie, obstétrique et biologie de la reproduction·R Slama, S Cordier
Dec 15, 2010·Experimental and Toxicologic Pathology : Official Journal of the Gesellschaft Für Toxikologische Pathologie·Patrícia Rosa de OliveiraMaria Izabel Camargo Mathias
Jul 19, 2008·Journal of Applied Toxicology : JAT·M F SimonielloM A Carballo
Feb 2, 2011·Paediatric and Perinatal Epidemiology·Adeleh ShirangiC D'Arcy J Holman
Sep 29, 2011·Birth Defects Research. Part A, Clinical and Molecular Teratology·Carissa M RocheleauJennita Reefhuis
Sep 3, 2014·Toxicology Mechanisms and Methods·Ibtissem Ben AmaraNajiba Zeghal
Jun 23, 2016·Iranian Red Crescent Medical Journal·Fatemeh SaraeiMohsen Foaddodini
Oct 8, 2005·Environmental Research·Parvathi K Basrur
Oct 25, 2001·American Journal of Industrial Medicine·L D MullS H Zahm
Dec 17, 2004·Human Reproduction Update·Edward V YounglaiWarren G Foster
Apr 12, 2006·Journal of Occupational and Environmental Medicine·Jin Liang ZhuJørn Olsen
Nov 10, 2001·Journal of Andrology·B F Hales, B Robaire
Jan 22, 2005·Birth Defects Research. Part C, Embryo Today : Reviews·Mary Frances McAleer, Rocky S Tuan

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