PET-CT with intravenous contrast in the evaluation of patients with lymphoma. Contribution to diagnostic indications

Revista española de medicina nuclear
M P Talavera RubioA Soriano Castrejón

Abstract

To define the utility of intravenous contrast administration in the PET-CT (PET-CTc) in patients with lymphoma in order to determine its possible indications. 78 patients with lymphoma were prospectively evaluated. All underwent simultaneous PET-CTc scans in a hybrid system for staging (8), evaluation of response to treatment (29), suspicion of recurrence (9) and complete remission control (48). The PET scan was acquired by a conventional method and the diagnostic CT scan was performed according to radiological protocol. Both examinations were evaluated blinded and independently, analyzing 28 anatomical locations in order to determine the degree of agreement. Final diagnosis was established by the clinician based on the histological study, results of other diagnostic techniques or clinical follow-up. The final result of both techniques were concordant in 87/94 studies (92.5%). A total of 158 (36 FP) pathological locations were detected with PET-CT and 189 (71 FP) with CTc, with 72 locations being discordant between both techniques. Global sensitivity, specificity, PPV and NPV were 93%, 98%, 77% and 99%; and 94%, 97%, 62% and 99%, respectively. Administration of intravenous contrast does not seem to provide any advantage in the ...Continue Reading

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Citations

Jul 12, 2011·Revista española de medicina nuclear e imagen molecular·A M García VicenteB Hernández Ruiz
Sep 25, 2010·Revista española de medicina nuclear·M P García AlonsoC Pey Illera

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