PET imaging for addiction medicine: From neural mechanisms to clinical considerations

Progress in Brain Research
Corinde E WiersGene-Jack Wang

Abstract

Positron emission tomography (PET) has been shown to be an effective imaging technique to study neurometabolic and neurochemical processes involved in addiction. That is, PET has been used to research neurobiological differences in substance abusers versus healthy controls and the pharmacokinetics and pharmacodynamics of abused drugs. Over the past years, the research scope has shifted to investigating neurobiological effects of abstinence and treatment, and their predictive power for relapse and other clinical outcomes. This chapter provides an overview of PET methodology, recent human PET studies on drug addiction and their implications for clinical treatment.

Citations

May 2, 2017·ACS Chemical Neuroscience·Guy A Higgins
Jun 24, 2017·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Corinde E WiersNora D Volkow
Sep 28, 2017·Nature Reviews. Neuroscience·Marco DianaAntonello Bonci
Mar 21, 2018·Journal of Neuroimmune Pharmacology : the Official Journal of the Society on NeuroImmune Pharmacology·Amna ZehraGene-Jack Wang
Sep 12, 2019·Physiological Reviews·Nora D VolkowRuben Baler
Jun 6, 2018·Frontiers in Physiology·Udita DattaRobert Huber
Feb 6, 2020·Focus : Journal of Life Long Learning in Psychiatry·Amna ZehraGene-Jack Wang
Jan 13, 2021·Translational Psychiatry·Victor Pando-NaudeEduardo A Garza-Villarreal
Feb 6, 2018·Biological Psychiatry : Cognitive Neuroscience and Neuroimaging·Rebecca J Houston, Nicolas J Schlienz

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