PET radiopharmaceuticals in Europe: current use and data relevant for the formulation of summaries of product characteristics (SPCs)

European Journal of Nuclear Medicine
G J MeyerB Langström

Abstract

The increasing use of radiopharmaceuticals for positron emission tomography (PET) has come to the attention of regulatory bodies. In order to help authorities in all aspects, the EANM has formed a task group for licensing PET radiopharmaceuticals; this group has surveyed the use of these compounds in Europe by a questionnaire. The number of PET centres that responded to the questionnaire was 26, which included more than 90% of the larger European PET centres. The survey showed that 2-[18f]fluoro-2-deoxyglucose is by far the most important pet radiopharmaceutical with more than 200 applications per week, followed by [15o]water, [15o]carbonmonoxide, [13n]ammonia, [11c]-l-methionine, and l-6-[18f]fluoro-dopa. More than 25 other PET radiopharmaceuticals are in regular use, however, at rather low application frequencies. The data were used by the European Pharmacopoeia Commission for its priority rating for requesting the formulation of monographs. Since it is likely that group registrations will be issued by authorities for the PET radiopharmaceuticals, relevant data on toxicity and dosimetry for the formulation of summaries of product characteristics have been collected by the task group as well.

References

Jan 1, 1992·European Journal of Nuclear Medicine·L JohanssonS Leide-Svegborn
Jul 1, 1992·Medical Physics·R MohanZ Fuks
May 1, 1991·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·K WienhardW D Heiss
Jan 1, 1990·International Journal of Radiation Applications and Instrumentation. Part A, Applied Radiation and Isotopes·A LuxenJ R Barrio
Jan 1, 1990·International Journal of Radiation Applications and Instrumentation. Part A, Applied Radiation and Isotopes·V W PikeD J Silvester
Jan 1, 1990·European Journal of Nuclear Medicine·W Huda, G A Sandison
Jan 1, 1987·International Journal of Radiation Applications and Instrumentation. Part A, Applied Radiation and Isotopes·J C ClarkK Strijckmans
Aug 1, 1988·The Science of the Total Environment·A K Haque, I A Al-Affan
Jan 1, 1984·Archives of Toxicology. Supplement. = Archiv Für Toxikologie. Supplement·M BaumannH Greim
Feb 1, 1983·Journal of Computer Assisted Tomography·K J KearfottB T Volpe

❮ Previous
Next ❯

Citations

Jul 1, 1997·European Journal of Nuclear Medicine·E BombardieriM Greco
Feb 2, 2012·Chemical & Pharmaceutical Bulletin·Jintaek KimMinoru Maeda
Sep 2, 1998·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·I C SmithO Eremin
Aug 12, 2014·BioMed Research International·V T Lien, P J Riss
Feb 9, 2002·Medical and Pediatric Oncology·Annemarie Elisabeth MüllerDieter Körholz
Oct 12, 2011·Chemical Communications : Chem Comm·Patrick J Riss, Franklin I Aigbirhio
Jul 27, 2012·Organic & Biomolecular Chemistry·Patrick J RissFranklin I Aigbirhio
Dec 31, 2019·Journal of Labelled Compounds & Radiopharmaceuticals·Anna BogniClaudio Pascali
Aug 20, 2010·Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine·Kun-Ju LinTzu-Chen Yen
May 27, 2021·EJNMMI Radiopharmacy and Chemistry·Klaudia A CybulskaPeter Laverman

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.