PMID: 9436557Jan 22, 1998Paper

PET scan predicts recovery of left ventricular function after coronary artery bypass operation

The Annals of Thoracic Surgery
W FlamengL Mortelmans

Abstract

Viable but hypocontractile myocardium can show functional improvement after revascularization (hibernation). It is sometimes difficult, however, to predict viability and recovery in patients with severe left ventricular function. This study sought to identify possible predictive factors of recovery of cardiac function after revascularization in patients with three-vessel disease. Positron emission tomography (fluoro-18-deoxyglucose uptake for metabolism; nitrogen 13-labeled ammonia for flow) and equilibrium-gated nuclear angiography (for the global ejection fraction) were performed in 59 patients with three-vessel disease before and after undergoing coronary artery bypass grafting. The positron emission tomographic data were expressed as match normal (flow and metabolism normal), mismatch (low flow, high metabolism), match viable (moderate decrease in flow and metabolism), and match necrosis (low flow and metabolism). Stepwise logistic regression analysis showed that only mismatch regions played a significant role in predicting postoperative improvement in function (p = 0.019). There were 1.7 +/- 1.5 mismatch regions in 31 patients who showed an improvement in their ejection fraction (0.47 +/- 0.14 versus 0.58 +/- 0.11; mean +/...Continue Reading

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Citations

Aug 9, 2012·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Senthil RajaB R Mittal
Apr 10, 2009·JACC. Cardiovascular Imaging·Shahbudin H RahimtoolaJean-Louis J Vanoverschelde
Oct 22, 2003·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Heinrich R SchelbertRandolph Patterson
Apr 4, 2006·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·James A Arrighi
Dec 19, 2006·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Josef MachacUNKNOWN Quality Assurance Committee of the American Society of Nuclear Cardiology
May 23, 2002·The Annals of Thoracic Surgery·Paul B JacklinMichael N Maisey
Aug 5, 2000·Clinics in Geriatric Medicine·M S Slaughter, H B Ward
Jun 30, 2001·Seminars in Nuclear Medicine·J A Parker
Oct 4, 2019·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Ganna DegtiarovaOlivier Gheysens
Dec 9, 1998·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·O JegadenP Mikaeloff
Feb 13, 2002·Seminars in Nuclear Medicine·Heinrich R Schelbert

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