PET/MRI for the evaluation of patients with lymphoma: initial observations

AJR. American Journal of Roentgenology
Laura HeacockHersh Chandarana

Abstract

The objective of our study was to assess the role of recently introduced hybrid PET/MRI in the evaluation of lymphoma patients using PET/CT as a reference standard. In this prospective study 28 consecutive lymphoma patients (18 men, 10 women; mean age, 53.6 years) undergoing clinically indicated PET/ CT were subsequently imaged with PET/MRI using residual FDG activity from the PET/ CT study. Blinded readers evaluated PET/CT (reference standard), PET/MRI, and diffusion-weighted imaging (DWI) studies separately; for each study, they assessed nodal and extranodal involvement. Each FDG-avid nodal station was marked and compared on DWI, PET/MRI, and PET/CT. Modified Ann Arbor staging was performed and compared between PET/MRI and PET/CT. The maximum standardized uptake value (SUVmax) on PET/MRI for FDG-avid nodal lesions was compared with the SUVmax on PET/CT. The apparent diffusion coefficient (ADC) for FDG-avid nodal lesions was compared to SUVmax on PET/MRI. Fifty-one FDG-avid nodal groups were identified on PET/CT in 13 patients. PET/MRI identified 51 of these nodal groups with a sensitivity of 100%. DWI identified 32 nodal groups for a sensitivity of 62.7%. PET/MRI staging and PET/CT staging were concordant in 96.4% of patients...Continue Reading

References

Jul 28, 2006·Annals of Hematology·Solène QuerellouOlivier Couturier
Jan 24, 2007·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Malik E JuweidUNKNOWN Imaging Subcommittee of International Harmonization Project in Lymphoma
Dec 14, 2007·Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine·Teruhiko TerasawaHirokazu Nagai
Sep 10, 2008·European Journal of Nuclear Medicine and Molecular Imaging·Kung-Chu HoTzu-Chen Yen
Apr 22, 2009·Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine·Martin Hutchings, Sally F Barrington
Dec 24, 2009·AJR. American Journal of Roentgenology·Carmel G CroninJohn F Bruzzi
Feb 16, 2011·Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine·Amanda F CashenNancy L Bartlett
Feb 24, 2011·AJR. American Journal of Roentgenology·Henriëtte M E Quarles van UffordJohn M H de Klerk
Apr 19, 2011·Acta Radiologica·Goran AbdulqadhrHåkan Ahlström
Apr 27, 2012·Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine·Alexander DrzezgaMarkus Schwaiger
Dec 1, 2012·European Journal of Nuclear Medicine and Molecular Imaging·Shonit PunwaniPaul D Humphries
Feb 26, 2013·European Journal of Nuclear Medicine and Molecular Imaging·Arthur VaroquauxMinerva Becker
Dec 7, 2013·Journal of Magnetic Resonance Imaging : JMRI·Thomas C KweeRutger A J Nievelstein
Feb 8, 2014·Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine·Philipp HeuschTill A Heusner

❮ Previous
Next ❯

Citations

Jun 18, 2016·Abdominal Radiology·Wendy AtkinsonAlexander R Guimaraes
Oct 23, 2015·AJR. American Journal of Roentgenology·Andrew B RosenkrantzRajan Jain
Nov 29, 2015·Magnetic Resonance Imaging Clinics of North America·Dow-Mu KohDavid J Collins
Mar 24, 2016·Pediatric Radiology·Maria Rosana PonisioGeetika Khanna
Feb 29, 2016·Current Hematologic Malignancy Reports·Kevin Barley, Ajai Chari
May 11, 2016·AJR. American Journal of Roentgenology·Sungheon Gene KimMari Hagiwara
Sep 7, 2016·PET Clinics·Ivan Platzek
Jul 18, 2016·Revista española de medicina nuclear e imagen molecular·C Riola-ParadaJ L Carreras-Delgado
Sep 15, 2016·Abdominal Radiology·Onofrio Antonio CatalanoBruce Robert Rosen
Apr 8, 2017·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Shannon M NavarroAaron J Schein
Jan 18, 2017·Korean Journal of Radiology : Official Journal of the Korean Radiological Society·Hina J ShahPamela J DiPiro
Nov 1, 2017·Journal of Magnetic Resonance Imaging : JMRI·Chiara GiraudoMarius E Mayerhoefer
Jul 2, 2019·Journal of Magnetic Resonance Imaging : JMRI·Marius E MayerhoeferHeiko Schöder
Dec 14, 2019·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Eman MarieReza Vali
Sep 20, 2020·Abdominal Radiology·Ryan D WardOnofrio Catalano
Mar 3, 2017·Nuclear Medicine and Molecular Imaging·Hyun Woo KwonGi Jeong Cheon
Mar 22, 2018·Revista da Associação Médica Brasileira·Marcelo A QueirozGiovanni Guido Cerri
Apr 17, 2020·Der Radiologe·Marius E Mayerhöfer, Alexander Haug
Feb 6, 2017·European Journal of Nuclear Medicine and Molecular Imaging·Julian KirchnerLale Umutlu
May 24, 2017·International Journal of Oncology·Onofrio Antonio CatalanoBruce Robert Rosen
Jun 28, 2018·The International Journal of Cardiovascular Imaging·L KamperP Haage
Apr 2, 2020·Der Radiologe·Krista Elise Suarez-WeissOnofrio A Catalano
May 20, 2020·Der Radiologe·Krista Elise Suarez-WeissOnofrio A Catalano
Apr 4, 2017·Journal of Magnetic Resonance Imaging : JMRI·Eric C EhmanThomas A Hope
Sep 9, 2016·Clinical Nuclear Medicine·Asim AfaqIrfan Kayani
Sep 1, 2017·Molecular and Clinical Oncology·Shunsuke SatoShinichi Konno
Feb 24, 2021·European Journal of Nuclear Medicine and Molecular Imaging·Jad S HusseiniOnofrio A Catalano
Jan 9, 2016·Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine·Claudio SpickJohannes Czernin
Oct 3, 2021·Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine·Lucia BarattoHeike E Daldrup-Link
Feb 21, 2021·Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine·Martijn V VerhagenPaul D Humphries

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.