PGI2 Is a Novel SGI1-Relative Multidrug-Resistant Genomic Island Characterized in Proteus mirabilis

Antimicrobial Agents and Chemotherapy
Chang-Wei LeiHong-Ning Wang

Abstract

A novel 61,578-bp genomic island named Proteus genomic island 2 (PGI2) was characterized in Proteus mirabilis of swine origin in China. The 23.85-kb backbone of PGI2 is related to those of Salmonella genomic island 1 and Acinetobacter genomic island 1. The multidrug resistance (MDR) region of PGI2 is a complex class 1 integron containing 14 different resistance genes. PGI2 was conjugally mobilized in trans to Escherichia coli in the presence of a conjugative IncC helper plasmid.

References

Aug 24, 2002·Journal of Bacteriology·Dietmar BöltnerA Mark Osborn
Apr 22, 2004·Nature Reviews. Microbiology·Ulrich DobrindtJörg Hacker
Mar 9, 2005·Molecular Microbiology·Benoît DoubletAxel Cloeckaert
Apr 30, 2008·Antimicrobial Agents and Chemotherapy·Renee S LevingsRuth M Hall
Jan 31, 2009·FEMS Microbiology Reviews·Mario JuhasDerrick W Crook
Aug 13, 2014·The Journal of Antimicrobial Chemotherapy·Eliane Siebor, Catherine Neuwirth
Sep 23, 2014·The Journal of Antimicrobial Chemotherapy·Delphine GirlichPatrice Nordmann
Oct 1, 2014·Antimicrobial Agents and Chemotherapy·Chang-Wei LeiDong-Dong Zhang
Apr 18, 2016·Current Opinion in Microbiology·Francisco Rodriguez-ValeraMario López-Pérez
Jun 16, 2016·MSphere·Christopher J Harmer, Ruth M Hall

❮ Previous
Next ❯

Citations

Oct 15, 2019·Frontiers in Microbiology·Xue-Chun WangHong-Ning Wang
Jan 7, 2021·Nucleic Acids Research·Mónika SzabóJános Kiss
Aug 4, 2020·International Journal of Antimicrobial Agents·Eliane Siebor, Catherine Neuwirth
Apr 13, 2021·Frontiers in Cellular and Infection Microbiology·Grzegorz CzerwonkaKatarzyna Durlik-Popińska

❮ Previous
Next ❯

Related Concepts

Related Feeds

CRISPR Screens in Drug Resistance

CRISPR-Cas system enables the editing of genes to create or correct mutations. This feed focuses on the application of CRISPR-Cas system in high-throughput genome-wide screens to identify genes that may confer drug resistance.

Aminoglycosides (ASM)

Aminoglycoside is a medicinal and bacteriologic category of traditional Gram-negative antibacterial medications that inhibit protein synthesis and contain as a portion of the molecule an amino-modified glycoside. Discover the latest research on aminoglycoside here.

Acinetobacter Infections

Acinetobacter infections have become common in hospitalized patients, especially in the intensive care unit setting and are difficult to treat due to their propensity to develop antimicrobial drug resistance. Discover the latest research on Acinetobacter Infections here.

Aminoglycosides

Aminoglycoside is a medicinal and bacteriologic category of traditional Gram-negative antibacterial medications that inhibit protein synthesis and contain as a portion of the molecule an amino-modified glycoside. Discover the latest research on aminoglycoside here.