pH- and redox-responsive polysaccharide-based microcapsules with autofluorescence for biomedical applications

Chemistry : a European Journal
Liang GaoJunbai Li

Abstract

Autofluorescent microcapsules were assembled by covalent cross-linking of polysaccharide alginate dialdehyde (ADA) derivative and cystamine dihydrochloride (CM) through a layer-by-layer (LBL) technique. The formulated Schiff base and disulfide bonds render capsules with pH- and redox-responsive properties for pinpointed intracellular delivery based on the physiological difference between intracellular and extracellular environments. This simple and versatile method could be extended to other polysaccharide derivatives for the fabrication of autofluorescent nano- and micromaterials with dual stimuli response for biomedical applications.

References

Jan 1, 1956·Advances in Carbohydrate Chemistry·J M BOBBITT
Sep 14, 2004·Biomacromolecules·Bingyun Li, Donald T Haynie
Jan 26, 2005·Langmuir : the ACS Journal of Surfaces and Colloids·Donald T HaynieNikhil Pargaonkar
Nov 1, 2005·Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy·Raafat M IssaHelen F Rizk
Mar 28, 2007·Chemical Society Reviews·Bruno G De GeestStefaan C De Smedt
Dec 13, 2007·Langmuir : the ACS Journal of Surfaces and Colloids·Xin Rong TengHelmuth Möhwald
Jul 26, 2008·Nature Nanotechnology·Dan PeerRobert Langer
Jul 29, 2008·Nanomedicine : Nanotechnology, Biology, and Medicine·Qinghe Zhao, Bingyun Li
Oct 9, 2008·Journal of the American Chemical Society·Baodui WangShouheng Sun
Nov 4, 2008·European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Für Pharmazeutische Verfahrenstechnik E.V·Vladimir Torchilin
Nov 5, 2008·Journal of the American Chemical Society·Wei WeiZhe-Yu Shen
Aug 1, 2007·ACS Nano·Alexander N ZelikinFrank Caruso
Aug 25, 2009·Advanced Drug Delivery Reviews·Francesca Greco, María J Vicent
Dec 22, 2009·Journal of the American Chemical Society·Ning MaXi Zhang
Jul 21, 2010·Nanoscale·Loretta L del MercatoWolfgang J Parak
Jul 21, 2010·Angewandte Chemie·Liesbeth J De CockMaria N Antipina
Oct 12, 2010·ACS Nano·Piyush ChaturbedyMuthusamy Eswaramoorthy
Nov 13, 2010·Chemical Communications : Chem Comm·Yi JiaJunbai Li
Nov 17, 2010·Journal of the American Chemical Society·Ja-Hyoung RyuS Thayumanavan
Feb 23, 2011·Chemistry : a European Journal·Chao WangXi Zhang
Mar 25, 2011·Advanced Materials·José A BarretoLeone Spiccia
Aug 10, 2011·Advanced Materials·Kang LiangFrank Caruso

❮ Previous
Next ❯

Citations

May 4, 2013·Advanced Drug Delivery Reviews·Carmen Alvarez-LorenzoAngel Concheiro
Nov 12, 2013·Advances in Colloid and Interface Science·Jiwei CuiFrank Caruso
Feb 13, 2016·Journal of Hazardous Materials·Shunlong PanLianjun Wang
Aug 21, 2015·ACS Applied Materials & Interfaces·Shaohua ZhangJiafu Shi
Aug 15, 2015·ACS Applied Materials & Interfaces·Zhanfeng LiXuejun Cui
Sep 11, 2016·Materials Science & Engineering. C, Materials for Biological Applications·Na CaoXueyan Zou
Oct 19, 2016·Journal of Colloid and Interface Science·Mingjun XuanJunbai Li
May 4, 2017·Biomacromolecules·Yifan DongKevin J Edgar
Aug 2, 2018·Soft Matter·Panpan SunLiqiang Zheng
Jun 15, 2012·Chemical Society Reviews·Weijun TongChangyou Gao
Aug 1, 2019·Chemical Communications : Chem Comm·Panpan SunLiqiang Zheng
Aug 26, 2017·Macromolecular Rapid Communications·Tingting YuanJunbai Li
Feb 20, 2014·Chemical Society Reviews·Rui R Costa, João F Mano
Jun 17, 2016·Chemical Record : an Official Publication of the Chemical Society of Japan ... [et Al.]·Xiyun FengJunbai Li
Nov 28, 2015·Journal of Materials Chemistry. B, Materials for Biology and Medicine·Arif GulzarJun Lin
Aug 25, 2015·Small·James J KwanConstantin C Coussios
Aug 10, 2013·Biomacromolecules·Dina MacielYulin Li
Feb 15, 2019·Langmuir : the ACS Journal of Surfaces and Colloids·Yi Jia, Junbai Li
Dec 6, 2014·ACS Applied Materials & Interfaces·Zhanfeng LiXuejun Cui
Sep 27, 2012·ACS Applied Materials & Interfaces·Guo-Feng LuoXian-Zheng Zhang

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.