PMID: 11345172May 10, 2001Paper

PH monitoring in the distal and proximal esophagus in symptomatic infants

Journal of Pediatric Gastroenterology and Nutrition
A AranaY Vandenplas

Abstract

Standard distal esophageal pH monitoring data are sometimes within normal ranges in children with clinically suspected gastroesophageal reflux disease. Therefore, the authors hypothesized that the amount of acid reflux reaching the proximal esophagus may be greater in some subgroups of patients than in healthy controls or in other subgroups of patients. The parameters of 24-hour pH monitoring in the proximal part of the esophagus were analyzed in 120 symptomatic infants in who the reflux parameters in the lower esophagus were clearly within normal ranges (reflux index < 5.0%). The infants were classified into four patient groups: excessive regurgitation (n = 41): inconsolable crying (n = 31), apparent life-threatening event (ALTE) (n = 18), and chronic respiratory disorders (n = 30). The control group consisted also of 120 infants. The following parameters were calculated: reflux index, the number of reflux episodes, the number of reflux episodes lasting longer than 5 minutes, the duration of the longest reflux episode, and the acid clearance time (ACT, duration of reflux episodes divided by number of reflux episodes). The patients with chronic respiratory disorders were significantly older than the patients in the other groups...Continue Reading

References

Apr 1, 1992·Journal of Pediatric Gastroenterology and Nutrition·Y VandenplasA Piepsz
Jan 1, 1988·Scandinavian Journal of Gastroenterology·P M Gustafsson, L Tibbling
Oct 21, 1998·Journal of Pediatric Gastroenterology and Nutrition·S C Ng, S H Quak
May 6, 1999·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·L A Halstead
May 6, 1999·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·S E SobolJ Ortenberg
Jun 3, 1999·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·B L MatthewsJ A Koufman
Jun 23, 1999·Developmental Medicine and Child Neurology·R E MortonJ Minford
Dec 2, 1999·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·S O UlualpR Shaker
Aug 2, 2000·Journal of Gastroenterology and Hepatology·Y Vandenplas, B Hegar
Sep 21, 2000·Journal of Pediatric Gastroenterology and Nutrition·B BaguckaY Vandenplas

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Citations

Apr 17, 2009·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·L CorvagliaG Faldella
Oct 4, 2005·Arquivos De Gastroenterologia·Helena Ayako Sueno GoldaniSergio Gabriel Silva de Barros

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