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pH properties and chemical mechanism of action of 3-hydroxy-3-methylglutaryl coenzyme A reductase

Biochemistry

Feb 17, 1981

D VelosoJames E Porter

PMID: 6783074

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Abstract

The pH variation of the kinetic parameters V and V/K for the oxidation of mevaldate by NADP+ in the presence of CoA (reverse reaction) and for the reduction of mevaldate by NADPH in the presence or absence of CoA (forward reaction) for the reactions catalyzed by 3-hydroxy-3-methylglutar...read more

Mentioned in this Paper

NADP
Ampholytes
Hydroxymethylglutaryl-CoA reductase
Hydrogen-Ion Concentration
Dimethylformamide
In Vivo NMR Spectroscopy
Sekumatic
Mevaldic acid, (+-)-isomer
Paper Details
References
  • References18
  • Citations13
12
  • References18
  • Citations13
12

pH properties and chemical mechanism of action of 3-hydroxy-3-methylglutaryl coenzyme A reductase

Biochemistry

Feb 17, 1981

D VelosoJames E Porter

PMID: 6783074

DOI:

Abstract

The pH variation of the kinetic parameters V and V/K for the oxidation of mevaldate by NADP+ in the presence of CoA (reverse reaction) and for the reduction of mevaldate by NADPH in the presence or absence of CoA (forward reaction) for the reactions catalyzed by 3-hydroxy-3-methylglutar...read more

Mentioned in this Paper

NADP
Ampholytes
Hydroxymethylglutaryl-CoA reductase
Hydrogen-Ion Concentration
Dimethylformamide

Related Papers

Paper Details
References
  • References18
  • Citations13
12
  • References18
  • Citations13
12

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