pH-Triggered softening of crosslinked hydrogen-bonded capsules

Soft Matter
Nils ElsnerAndreas Fery

Abstract

We report here the first AFM single capsule mechanical measurements on hydrogen-bonded polymeric multilayer microcapsules made of poly(vinylpyrrolidone)/poly(methacrylic acid) (PVPON/PMAA) and of poly(-vinylpyrrolidone-co-NH-20)/poly(methacrylic acid) (PVPON-co-NH-20/PMAA), as well as of capsules derived from these systems chemical crosslinking. The stiffness of the non-crosslinked hydrogen-bonded capsules was found to be proportional to the square of the wall thickness which is in agreement with previous observations on other multilayer capsules and continuum mechanical theory. The found elastic modulus of 610 MPa for low pH (= 2) is typical for a highly stable, glass-like structure similar to electrostatically bound multilayers. At pH > 6, (PMAA) capsules obtained through chemical crosslinking of hydrogen-bonded (PVPON/PMAA) multilayers, or crosslinked (PVPON-co-NH-20/PMAA) capsules showed a sharp hundreds-fold stiffness decrease to ∼1 mN/m which was orders of magnitude lower than those reported earlier for polymeric multilayer systems. pH-Triggered softening was reversible and highly reproducible. Softening of both (PMAA) and (PVPON-co-NH-20/PMAA) crosslinked capsules resulted from increased PMAA ionization, and additional d...Continue Reading

References

Mar 30, 2000·Journal of Microencapsulation·G B SukhorukovH Möhwald
Mar 10, 2004·The European Physical Journal. E, Soft Matter·F DubreuilA Fery
Aug 11, 2004·Langmuir : the ACS Journal of Surfaces and Colloids·Christophe Déjugnat, Gleb B Sukhorukov
Dec 2, 2004·Advances in Colloid and Interface Science·Alexei A Antipov, Gleb B Sukhorukov
Dec 29, 2004·Langmuir : the ACS Journal of Surfaces and Colloids·Huiguang Zhu, Michael J McShane
Mar 23, 2005·Langmuir : the ACS Journal of Surfaces and Colloids·J HeuvinghA Fery
Jun 1, 2005·Langmuir : the ACS Journal of Surfaces and Colloids·Mi-Kyoung ParkRigoberto C Advincula
Dec 8, 2005·Journal of the American Chemical Society·Jodie L LutkenhausPaula T Hammond
Feb 8, 2006·Langmuir : the ACS Journal of Surfaces and Colloids·Sung Yun YangMichael F Rubner
Feb 8, 2006·Langmuir : the ACS Journal of Surfaces and Colloids·Zhijie Sui, Joseph B Schlenoff
Mar 2, 2006·Journal of the American Chemical Society·Jad A Jaber, Joseph B Schlenoff
Jun 14, 2006·Langmuir : the ACS Journal of Surfaces and Colloids·Tatjana MauserGleb B Sukhorukov
Jun 14, 2006·Langmuir : the ACS Journal of Surfaces and Colloids·Solar C OlugebefolaAnne M Mayes
Sep 4, 1998·Angewandte Chemie·Edwin DonathHelmuth Möhwald
Sep 26, 2005·Soft Matter·Junbai LiGang Lu

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Citations

Nov 14, 2007·Soft Matter·Alexander Alexeev, Anna C Balazs
Jun 20, 2008·Soft Matter·Veronika KozlovskayaSvetlana A Sukhishvili
Oct 1, 2010·Chemical Society Reviews·Georgina K SuchFrank Caruso
Feb 21, 2008·Soft Matter·Sheng DaiKam Chiu Tam
Jul 28, 2007·The Journal of Chemical Physics·Guangdong ZhuAnna C Balazs
Jun 23, 2011·Chemical Communications : Chem Comm·Veronika KozlovskayaEugenia Kharlampieva
Oct 15, 2013·Advanced Materials·Joseph J RichardsonFrank Caruso
Nov 28, 2012·Advanced Healthcare Materials·James P BestFrank Caruso
May 7, 2014·Journal of Materials Chemistry. B, Materials for Biology and Medicine·Veronika KozlovskayaEugenia Kharlampieva
Jan 7, 2017·Journal of Materials Chemistry. B, Materials for Biology and Medicine·Bing XueEugenia Kharlampieva
Jun 24, 2008·The Journal of Chemical Physics·O Berk UstaAnna C Balazs
Feb 16, 2021·Chemical Communications : Chem Comm·Angana Borbora, Uttam Manna
Apr 22, 2009·Langmuir : the ACS Journal of Surfaces and Colloids·Emmanouil GlynosVassilis Sboros
Dec 3, 2009·Langmuir : the ACS Journal of Surfaces and Colloids·Gaulthier RydzekFouzia Boulmedais
Sep 21, 2007·Langmuir : the ACS Journal of Surfaces and Colloids·O Berk UstaAnna C Balazs
Jul 9, 2010·Langmuir : the ACS Journal of Surfaces and Colloids·Nicola C WoodwardVictor J Morris
Jun 27, 2012·Langmuir : the ACS Journal of Surfaces and Colloids·Qiangying YiGleb B Sukhorukov
Mar 3, 2012·Langmuir : the ACS Journal of Surfaces and Colloids·Shupeng SheChangyou Gao
May 14, 2016·Langmuir : the ACS Journal of Surfaces and Colloids·Sandrine Le TirillyCécile Monteux
Jul 28, 2012·Langmuir : the ACS Journal of Surfaces and Colloids·Chunhong YeVladimir V Tsukruk
May 23, 2014·ACS Nano·Veronika KozlovskayaEugenia Kharlampieva
Aug 2, 2011·Langmuir : the ACS Journal of Surfaces and Colloids·Milana O LisunovaVladimir V Tsukruk
Jul 28, 2013·Langmuir : the ACS Journal of Surfaces and Colloids·James P BestFrank Caruso
Jul 28, 2013·Langmuir : the ACS Journal of Surfaces and Colloids·James P BestFrank Caruso
Sep 26, 2013·Biomacromolecules·Jun ChenEugenia Kharlampieva
Apr 12, 2012·ACS Nano·Irina DrachukVladimir V Tsukruk
Nov 5, 2011·Biomacromolecules·Chunhong YeVladimir V Tsukruk
Jul 30, 2019·Langmuir : the ACS Journal of Surfaces and Colloids·Nirzari GuptaEugenia Kharlampieva
Mar 24, 2020·ACS Sensors·Julia Ann-Therese WalkerSimon R Corrie
Jun 13, 2017·ACS Applied Materials & Interfaces·Ekaterina LengertBogdan Parakhonskiy

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