pH-zone-refining countercurrent chromatography

Journal of Chromatography. a
Y Ito, Y Ma

Abstract

A recently developed preparative technique, pH-zone-refining countercurrent chromatography (CCC), separates organic acids and bases according to their pKa and hydrophobicity. The hydrodynamic mechanism of pH-zone-refining CCC is illustrated in two elution modes along with a simple mathematical analysis. Separations include acidic and basic derivatives of amino acids and peptides, hydroxyxanthene dyes, alkaloids, indole auxins, and structural and geometrical isomers. In addition, recently developed affinity ligand separations of enantiomers, polar catecholamines, and free peptides are also described. Technical guidance is provided for interested users so that they can conduct a systematic search for the optimum solvent system and experimental conditions. Advantages as well as limitations of the present technique are discussed.

References

Jan 18, 1991·Journal of Chromatography·H J CahnmannE A Sokoloski
Jul 3, 1970·Science·T TanimuraR L Bowman
Sep 1, 1995·Analytical Chemistry·Y Ma, Y Ito

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Citations

Sep 7, 2013·Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences·Mahmoud HamzaouiJane Hubert
Jun 19, 2013·Critical Reviews in Food Science and Nutrition·Rohit Upadhyay, L Jagan Mohan Rao
Jul 15, 2015·Analytical Chemistry·Guido F PauliJ Brent Friesen
Sep 15, 2010·Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences·Yun WeiYoichiro Ito
Jul 16, 2015·Journal of Natural Products·J Brent FriesenGuido F Pauli
May 12, 2009·Journal of Chromatography. a·Chun-Xia ZhaoChao-Hong He
Feb 11, 2009·Journal of Chromatography. a·J B Friesen, G F Pauli
Nov 10, 2015·Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences·Mahinur BakriHaji Akber Aisa
Aug 5, 2005·Journal of Chromatography. a·N Savitri Kumar, Maheshinie Rajapaksha
May 6, 2015·Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences·Genlai DongYun Wei
Mar 7, 2015·Journal of Chromatography. a·Sébastien CholletAlain Foucault
Aug 11, 2006·Organic Letters·Alix ToribioJean-Hugues Renault
Jan 18, 2006·Journal of Chromatography. a·Eva PérezCristina Minguillón
Sep 8, 2011·Journal of Separation Science·Lei FangLuqi Huang
Mar 29, 2011·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Xia XuZhang-Fa Yang
Jul 20, 2007·Journal of Separation Science·Shengqiang TongJianzhong Lou

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