Phaeophytin analogues from Ligularia knorringiana.

Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry
Hui LiQi Wang

Abstract

A new phaeophytin, ligulariaphytin A, together with five known phaeophytins, were isolated from the aerial parts of Ligularia knorringiana. The structure of ligulariaphytin A was elucidated as 13¹-hydroxy-13¹,13²-peroxyphaeophorbide A ethyl ester, and the five known compounds were identified as 13²-hydroxyphaeophorbide A ethyl ester, 17³-ethoxyphaeophorbide A, phaeophytin B, phaeophytin A, and phaeophorbide B ethyl ester, respectively, based on spectroscopic analysis and by comparison of their spectral data with those reported previously in the literature. All compounds were evaluated for their in vitro cytotoxic activities against cultured Hela cell, and were found to show only very weak cytotoxicity.

References

Jul 2, 2004·Organic Letters·Quan-Xiang WuLi Yang
Dec 29, 2006·Chemistry & Biodiversity·Chin-Fei CheeAnthony Siong-Hock Ho
Sep 14, 2007·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Xinping HuangWenhan Lin
Jan 16, 2010·Journal of Natural Products·Qi WangDao-Feng Chen

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Citations

Apr 20, 2019·Marine Drugs·Sara FreitasRalph Urbatzka
Oct 5, 2019·Natural Product Research·Camila Macaúbas-SilvaYanna C F Teles

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Methods Mentioned

BETA
column
NMR

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