Phage-Based Applications in Synthetic Biology

Annual Review of Virology
Sebastien LemireTimothy K Lu

Abstract

Bacteriophage research has been instrumental to advancing many fields of biology, such as genetics, molecular biology, and synthetic biology. Many phage-derived technologies have been adapted for building gene circuits to program biological systems. Phages also exhibit significant medical potential as antibacterial agents and bacterial diagnostics due to their extreme specificity for their host, and our growing ability to engineer them further enhances this potential. Phages have also been used as scaffolds for genetically programmable biomaterials that have highly tunable properties. Furthermore, phages are central to powerful directed evolution platforms, which are being leveraged to enhance existing biological functions and even produce new ones. In this review, we discuss recent examples of how phage research is influencing these next-generation biotechnologies.

References

Oct 1, 1988·Virology·C Hashimoto, H Fujisawa
Apr 1, 1967·Proceedings of the National Academy of Sciences of the United States of America·B Weiss, C C Richardson
Feb 5, 2000·Nature·M B Elowitz, S Leibler
Jun 10, 2003·Microbiology and Molecular Biology Reviews : MMBR·Carlos CanchayaHarald Brüssow
Jul 29, 2003·Progress in Nucleic Acid Research and Molecular Biology·Rui Sousa, Srabani Mukherjee
May 1, 1952·The Journal of General Physiology·A D HERSHEY, M CHASE
Feb 1, 1953·Journal of Bacteriology·G BERTANI, J J WEIGLE
Dec 30, 1961·Nature·F H CRICKR J WATTS-TOBIN
Feb 28, 2006·Science and Engineering Ethics·R R Kishore
Mar 24, 2007·Science·Rodolphe BarrangouPhilippe Horvath
Jun 27, 2007·Proceedings of the National Academy of Sciences of the United States of America·Timothy K Lu, James J Collins
Feb 12, 2008·Current Protocols in Molecular Biology·Lynn ThomasonAmos Oppenheim
Oct 1, 2008·Current Opinion in Microbiology·Graham F Hatfull
Oct 28, 2008·Biological Chemistry·Gary T Jennings, Martin F Bachmann
Feb 3, 2009·Current Opinion in Structural Biology·Ann Hochschild, Mitchell Lewis
Apr 14, 2009·Nature Methods·Daniel G GibsonHamilton O Smith
May 12, 2009·Advances in Applied Microbiology·E J AllanJ Gumpert
Jan 1, 2009·Current Pharmaceutical Biotechnology·Elizabeth KutterStephen T Abedon
Jun 24, 2010·Biosecurity and Bioterrorism : Biodefense Strategy, Practice, and Science·Flavie PouillotFrançois Iris
Jul 14, 2010·Applied and Environmental Microbiology·Mathias SchmelcherMartin J Loessner
Apr 12, 2011·Nature·Kevin M EsveltDavid R Liu
Sep 14, 2011·Microbial Biotechnology·Tamás FehérGyörgy Pósfai
Jun 9, 2012·Proceedings of the National Academy of Sciences of the United States of America·Petra LukacikSusan K Buchanan
Jun 30, 2012·Nucleic Acids Research·Karsten TemmeChristopher A Voigt
Jul 4, 2012·Advances in Virus Research·Andrzej GórskiDanuta Kłosowska
Jul 26, 2012·Biomacromolecules·Jin-Kyu RheeM G Finn
Oct 11, 2012·Bacteriophage·William C Summers
Nov 1, 2012·Molecular Pharmaceutics·Francis A Galaway, Peter G Stockley
Feb 12, 2013·Nature Biotechnology·Piro SiutiTimothy K Lu
May 17, 2013·Nature·Ramiz DanielTimothy K Lu

❮ Previous
Next ❯

Citations

Apr 11, 2019·The Journal of Gene Medicine·Tianying LuoYu Nie
Apr 17, 2020·Viruses·Floriane LaumayCécile Breyton
May 28, 2019·Frontiers in Microbiology·Yibao ChenPan Tao
Jun 26, 2020·Frontiers in Microbiology·Jean-Paul Pirnay
Aug 21, 2020·Scientific Reports·Andrew H FavorJorge A Bardales
Jun 6, 2019·Methods and Protocols·Jae-Yeol LeeYou-Hee Cho
Jan 8, 2020·Virus Evolution·Benjamin R JackClaus O Wilke
Oct 22, 2020·Nature Communications·Eveline-Marie LammensRob Lavigne
Dec 11, 2020·Life Sciences·Yingli JingYan Yu
Dec 15, 2020·Current Opinion in Biotechnology·Bryan R LennemanSamuel Kilcher
Mar 10, 2021·Current Microbiology·Taruna AnandBhupendra N Tripathi
Mar 11, 2021·Periodontology 2000·Szymon P SzafrańskiMeike Stiesch
Apr 6, 2021·Synthetic Biology·Mingqi XieMartin Fussenegger
Jun 10, 2021·FEMS Microbiology Reviews·Rodrigo Ibarra-ChávezUrvish Trivedi
Jul 3, 2021·International Journal of Molecular Sciences·Ho Yin Pekkle LamKai-Chih Chang
Jun 23, 2020·Journal of Controlled Release : Official Journal of the Controlled Release Society·Peter J VoorheesSamuel K Lai
Jul 27, 2021·Frontiers in Microbiology·Sangryeol Ryu
Sep 2, 2021·Open Biology·Véronique OngenaeDennis Claessen
Nov 19, 2021·Environmental Science & Technology·Cory SchwarzPedro J J Alvarez
Jan 6, 2022·ACS Synthetic Biology·Chutikarn ChitboonthavisukSrivatsan Raman

❮ Previous
Next ❯

Methods Mentioned

BETA
two
new hybrid
in vitro transcription
PCR
phage display

Software Mentioned

Lysando
PACE
ELITA
GangaGen

Related Concepts

Related Feeds

Bacteriophage: Phage Therapy

Phage therapy uses bacterial viruses (bacteriophages) to treat bacterial infections and is widely being recognized as an alternative to antibiotics. Here is the latest research.

Biomaterial Engineering

Advances in biomaterial engineering have permitted the development of sophisticated drug-releasing materials with a biomimetic 3D support that allow a better control of the microenvironment of transplanted cells. Here is the latest research.

Bioinformatics in Biomedicine

Bioinformatics in biomedicine incorporates computer science, biology, chemistry, medicine, mathematics and statistics. Discover the latest research on bioinformatics in biomedicine here.

Related Papers

Sheng wu gong cheng xue bao = Chinese journal of biotechnology
Fangyuan WangLei Stanley Qi
Nihon rinsho. Japanese journal of clinical medicine
Hayato Miyachi
© 2022 Meta ULC. All rights reserved