Phages and the evolution of bacterial pathogens: from genomic rearrangements to lysogenic conversion

Microbiology and Molecular Biology Reviews : MMBR
Harald BrüssowWolf-Dietrich Hardt

Abstract

Comparative genomics demonstrated that the chromosomes from bacteria and their viruses (bacteriophages) are coevolving. This process is most evident for bacterial pathogens where the majority contain prophages or phage remnants integrated into the bacterial DNA. Many prophages from bacterial pathogens encode virulence factors. Two situations can be distinguished: Vibrio cholerae, Shiga toxin-producing Escherichia coli, Corynebacterium diphtheriae, and Clostridium botulinum depend on a specific prophage-encoded toxin for causing a specific disease, whereas Staphylococcus aureus, Streptococcus pyogenes, and Salmonella enterica serovar Typhimurium harbor a multitude of prophages and each phage-encoded virulence or fitness factor makes an incremental contribution to the fitness of the lysogen. These prophages behave like "swarms" of related prophages. Prophage diversification seems to be fueled by the frequent transfer of phage material by recombination with superinfecting phages, resident prophages, or occasional acquisition of other mobile DNA elements or bacterial chromosomal genes. Prophages also contribute to the diversification of the bacterial genome architecture. In many cases, they actually represent a large fraction of th...Continue Reading

References

Feb 1, 1977·Journal of Virology·L LinG Edlin
Feb 1, 1977·Journal of Virology·G EdlinR Bitner
Jun 1, 1978·Microbiological Reviews·M M Susskind, D Botstein
Dec 1, 1992·Journal of Bacteriology·A M Campbell
Nov 1, 1991·Journal of Clinical Microbiology·L M McCroskeyP Jurgenson
Sep 1, 1989·Proceedings of the National Academy of Sciences of the United States of America·B Canard, S T Cole
May 1, 1987·Proceedings of the National Academy of Sciences of the United States of America·R K TaylorJ J Mekalanos
Sep 1, 1985·Infection and Immunity·G A BuckN Groman
Jul 12, 1985·Science·M J Betley, J J Mekalanos
Jul 1, 1987·Proceedings of the National Academy of Sciences of the United States of America·S B CalderwoodJ J Mekalanos
Oct 1, 1987·Journal of Bacteriology·S B Calderwood, J J Mekalanos
Aug 1, 1986·The Journal of Infectious Diseases·P AureliC L Hatheway
Jan 1, 1974·Annual Review of Microbiology·L Barksdale, S B Arden
Jan 5, 1972·Nature: New Biology·M W EklundS M Reed
Jun 28, 1968·Journal of Molecular Biology·K OkamotoJ Marmur
Sep 1, 1971·Nature: New Biology·T UchidaA M Pappenheimer
Jan 1, 1980·Annals of the New York Academy of Sciences·D Botstein
May 1, 1995·Infection and Immunity·Y ZhouE A Johnson
Apr 1, 1995·Applied and Environmental Microbiology·P Schicklmaier, H Schmieger
Sep 1, 1993·Molecular Microbiology·P RoggentinE R Vimr
Nov 1, 1995·Applied and Environmental Microbiology·J D BoyceA J Hillier
Jun 28, 1996·Science·M K Waldor, J J Mekalanos

❮ Previous
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Citations

Jul 30, 2010·Cellular and Molecular Life Sciences : CMLS·Natalia Malachowa, Frank R DeLeo
Jun 19, 2010·Archives of Microbiology·Monika GlinkowskaMarcin Loś
Mar 2, 2010·Applied Microbiology and Biotechnology·Matthias Brigulla, Wilfried Wackernagel
Dec 8, 2009·Current Microbiology·Ramin Mazaheri Nezhad FardMichael W Heuzenroeder
Jun 26, 2010·Current Microbiology·Irene L G Newton, Seth R Bordenstein
Mar 4, 2011·Molecular Genetics and Genomics : MGG·O Ludvig NyquistIngolf F Nes
Sep 18, 2010·Archives of Virology·Se Hwan JangHyo-Ihl Chang
Feb 15, 2011·Archives of Virology·Young-Duck LeeJong-Hyun Park
Mar 17, 2007·Biotechnology Letters·Mikael SkurnikSaija Kiljunen
Jan 30, 2008·Origins of Life and Evolution of the Biosphere : the Journal of the International Society for the Study of the Origin of Life·Matti Jalasvuori, Jaana K H Bamford
Sep 21, 2012·Folia Microbiologica·František GolaisJana Vítkovská
Apr 6, 2005·FEMS Microbiology Reviews·David A RaskoJacques Ravel
Apr 2, 2013·Trends in Microbiology·Paul HymanPaul Barrow
May 21, 2013·Trends in Microbiology·Yu TanouchiLingchong You
May 7, 2013·Veterinary Microbiology·Andrew S Waller
Oct 19, 2010·Epidemiology and Infection·M Price-CarterP E Carter
Mar 2, 2006·The Journal of Antibiotics·Thomas G Kinscherf, David K Willis
Apr 2, 2011·Nature·Elitza DeltchevaEmmanuelle Charpentier
Jan 27, 2011·Nature Communications·Xiaoxue WangThomas K Wood
Sep 17, 2013·Nature Communications·Lesley A OgilvieBrian V Jones
Feb 4, 2010·Nature Reviews. Genetics·Luciano A Marraffini, Erik J Sontheimer
Sep 3, 2005·Nature Reviews. Microbiology·Laura S FrostAriane Toussaint
Dec 28, 2006·Nature Reviews. Microbiology·Charles J Dorman
Jan 5, 2011·Nature Reviews. Microbiology·Marilyn J Roossinck
Jun 12, 2012·Nature Reviews. Microbiology·Andrew S LangJ Thomas Beatty
Aug 15, 2008·Proceedings of the National Academy of Sciences of the United States of America·Wei WeiYan Zhao
Mar 6, 2012·Proceedings of the National Academy of Sciences of the United States of America·Marcia F MarstonJennifer B H Martiny
Aug 14, 2013·Proceedings of the National Academy of Sciences of the United States of America·Rachid MenouniMireille Ansaldi
Sep 13, 2011·The Journal of Biological Chemistry·Stéphanie ChampMireille Ansaldi
May 18, 2012·Critical Reviews in Food Science and Nutrition·Sara R MililloSteven C Ricke
Jun 22, 2005·The Journal of Experimental Medicine·Emmanuelle BilleColin R Tinsley
Jan 9, 2008·The Journal of Infectious Diseases·Ivo VojtekEmmanuelle Charpentier
Dec 22, 2005·Foodborne Pathogens and Disease·A D BrabbanT R Callaway
May 13, 2011·Foodborne Pathogens and Disease·Caterina GrazianiIda Luzzi
Oct 10, 2013·Foodborne Pathogens and Disease·Federico CapuanoYolande T R Proroga
Apr 20, 2013·Journal of Aerosol Medicine and Pulmonary Drug Delivery·Susan HoeReinhard Vehring
Mar 23, 2013·Briefings in Functional Genomics·Jochen KlumppShanmuga Sozhamannan
Feb 23, 2012·Genome Biology and Evolution·Eduardo Castro-NallarP Scott Chandry
Aug 6, 2011·The Journal of Antimicrobial Chemotherapy·Jean Marc RolainDidier Raoult
Dec 18, 2012·Molecular Biology and Evolution·Louis-Marie BobayMarie Touchon

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