Phantom-calibrated versus automatic coronary artery mass quantification with multidetector-row computed tomography: in vitro and in vivo study

Acta Radiologica
Z SerafinK Laskowska

Abstract

Coronary artery calcium scoring is used as a method for cardiovascular risk stratification and monitoring of coronary heart disease. Automatic software-based calcium mass calculation has been proposed to improve the performance of the procedure. To compare two algorithms of calcium mass measurement, automatic and phantom calibrated, with respect to correlation, measurement error, and accuracy in vitro and in vivo. A cardiac phantom with calcium cylinder inserts was scanned with sequential non-overlapping collimation 4 x 2.5 mm, at 120 kV and 165 mAs. Fifty adults (37 men; mean age 46.2 years) were examined with the same settings using prospective electrocardiographic triggering to detect and quantify coronary artery calcifications. Calculations were performed with two methods: software-based automatic calcium mass measurement (ACM) and phantom-calibrated calcium mass measurement (CCM). The total phantom calcium masses measured with ACM and CCM were 175.0+/-13.8 mg and 163.0+/-4.4 mg, respectively (P<0.0001), and ACM produced a higher mean error (4.5 vs. 3.2; P<0.05). Results of ACM and CCM were strongly correlated to each other (R=0.73-0.96; P<0.0001). Mean image noise in the patient study was 8.72+/-1.68 HU. Results of patient...Continue Reading

Citations

Jan 21, 2012·Journal of Computer Assisted Tomography·Zbigniew SerafinWładysław Lasek

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