Phantom tones and suppressive masking by active nonlinear oscillation of the hair-cell bundle.

Proceedings of the National Academy of Sciences of the United States of America
Jérémie Barral, Pascal Martin

Abstract

Processing of two-tone stimuli by the auditory system introduces prominent masking of one frequency component by the other as well as additional "phantom" tones that are absent in the sound input. Mechanical correlates of these psychophysical phenomena have been observed in sound-evoked mechanical vibrations of the mammalian cochlea and are thought to originate in sensory hair cells from the intrinsic nonlinearity associated with mechano-electrical transduction by ion channels. However, nonlinearity of the transducer is not sufficient to explain the rich phenomenology of two-tone interferences in hearing. Here we show that active oscillatory movements of single hair-cell bundles elicit two-tone suppression and distortions that are shaped by nonlinear amplification of periodic stimuli near the characteristic frequency of spontaneous oscillations. When both stimulus frequencies enter the bandwidth of the hair-bundle amplifier, two-tone interferences display level functions that are characteristic both of human psychoacoustics and of in vivo mechanical measurements in auditory organs. Our work distinguishes the frequency-dependent nonlinearity that emerges from the active process that drives the hair bundle into spontaneous oscill...Continue Reading

References

May 1, 1991·The Journal of the Acoustical Society of America·R ProbstG K Martin
Oct 1, 1989·Hearing Research·R B PatuzziB M Johnstone
Mar 1, 1967·The Journal of the Acoustical Society of America·J L Goldstein
Aug 5, 1993·Nature·F JaramilloA J Hudspeth
Apr 1, 1996·The Journal of the Acoustical Society of America·R Nobili, F Mammano
May 1, 1997·Journal of Neurophysiology·L RoblesN C Rich
Dec 23, 1998·Proceedings of the National Academy of Sciences of the United States of America·Y ChoeA J Hudspeth
Dec 10, 1999·Proceedings of the National Academy of Sciences of the United States of America·P Martin, A J Hudspeth
Mar 29, 2000·Proceedings of the National Academy of Sciences of the United States of America·S CamaletJ Prost
Sep 16, 2000·Physical Review Letters·V M EguíluzM O Magnasco
Oct 12, 2000·Proceedings of the National Academy of Sciences of the United States of America·P MartinA J Hudspeth
Feb 28, 2001·Proceedings of the National Academy of Sciences of the United States of America·G A ManleyG K Yates
Jun 28, 2001·Physiological Reviews·L Robles, M A Ruggero
Aug 2, 2001·Proceedings of the National Academy of Sciences of the United States of America·F JülicherT Duke
Aug 10, 2001·Journal of Neurophysiology·G A Manley
Nov 29, 2001·Proceedings of the National Academy of Sciences of the United States of America·P Martin, A J Hudspeth
Nov 29, 2001·Proceedings of the National Academy of Sciences of the United States of America·P MartinF Jülicher
Apr 23, 2004·Journal of Neurophysiology·Geoffrey A ManleyChristine Köppl
May 26, 2004·Hearing Research·Sebastiaan W F Meenderink, Pim van Dijk
Aug 11, 2004·Proceedings of the National Academy of Sciences of the United States of America·Björn NadrowskiFrank Jülicher
Oct 14, 2004·The Journal of the Acoustical Society of America·M C LibermanJ J Guinan
Jan 12, 2005·Nature Neuroscience·Dylan K Chan, A J Hudspeth
Jan 22, 2005·The Journal of the Acoustical Society of America·Pantelis N VassilakisPeter M Narins
Aug 21, 2007·Biophysical Journal·Jean-Yves TinevezPascal Martin
Jan 16, 2008·Physiological Reviews·Jonathan Ashmore
Jun 3, 2008·Nature Neuroscience·Marcia M Mellado LagardeIan J Russell
Nov 19, 2008·Proceedings of the National Academy of Sciences of the United States of America·Kai DierkesFrank Jülicher
Aug 25, 2009·The European Physical Journal. E, Soft Matter·F JülicherP Martin
Apr 21, 2010·Proceedings of the National Academy of Sciences of the United States of America·Jérémie BarralPascal Martin
May 1, 2010·Hearing Research·Anthony W Peng, Anthony J Ricci
Jun 12, 2010·Journal of Neurophysiology·A J HudspethPascal Martin
Jun 15, 2010·Hearing Research·J AshmoreB Canlon
Sep 8, 2010·The Journal of the Acoustical Society of America·Dáibhid O Maoiléidigh, Frank Jülicher
Aug 10, 2011·Current Opinion in Otolaryngology & Head and Neck Surgery·Jérémie Barral, Pascal Martin

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Citations

Aug 21, 2014·Biophysical Journal·Pascal Martin
Oct 1, 2013·Current Biology : CB·Natasha Mhatre, Daniel Robert
Feb 19, 2015·Proceedings of the National Academy of Sciences of the United States of America·Joshua D SalviA J Hudspeth
Dec 17, 2014·Journal of Comparative Physiology. A, Neuroethology, Sensory, Neural, and Behavioral Physiology·Natasha Mhatre
Aug 7, 2014·Nature Reviews. Neuroscience·A J Hudspeth
Feb 8, 2018·Royal Society Open Science·James F C WindmillDaniel Robert
Oct 19, 2013·Physiological Reviews·Paul AvanChristine Petit
Jul 10, 2014·Reports on Progress in Physics·Tobias Reichenbach, A J Hudspeth
Oct 17, 2018·Cold Spring Harbor Perspectives in Medicine·Dolores Bozovic
Oct 12, 2018·Nature Communications·Alfred L NuttallAnders Fridberger
Aug 2, 2018·Psychonomic Bulletin & Review·I-Hui Hsieh, Jia-Wei Liu
Mar 26, 2016·Physical Review Letters·Florian GomezRuedi Stoop
Jan 23, 2020·Communications Biology·Tianying Ren, Wenxuan He

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