Pharmaceutical prospects of naturally occurring quinazolinone and its derivatives

Fitoterapia
Dan HeYuanyan Liu

Abstract

Quinazolinones belong to a family of heterocyclic nitrogen compounds that have attracted increasing interest because of their broad spectrum of biological functions. This review describes three types of natural quinazolinones and their synthesized derivatives and summarizes their various pharmacological activities, including antifungal, anti-tumor, anti-malaria, anticonvulsant, anti-microbial, anti-inflammatory and antihyperlipidemic activities. In addition, structure-activity relationships of quinazolinone derivatives are also reviewed.

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Citations

Aug 28, 2019·Organic & Biomolecular Chemistry·Seohoo LeeJae-Kyung Jung
Oct 24, 2019·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Amira A El-SayedAhmed M Naglah
Jun 19, 2020·Metabolites·Yaojie GuoThomas O Larsen
Mar 17, 2019·International Journal of Molecular Sciences·Natalia Piekuś-SłomkaStanisław Sobiak
Feb 8, 2019·Journal of Industrial Microbiology & Biotechnology·Nataliia V MachushynetsGilles P van Wezel
Jan 14, 2021·International Journal of Molecular Sciences·Jana HricovíniováKatarína Kozics

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