Pharmaceutical residues are widespread in Baltic Sea coastal and offshore waters - Screening for pharmaceuticals and modelling of environmental concentrations of carbamazepine

The Science of the Total Environment
Berndt BjörleniusJerker Fick

Abstract

The consumption of pharmaceuticals worldwide coupled with modest removal efficiencies of sewage treatment plants have resulted in the presence of pharmaceuticals in aquatic systems globally. In this study, we investigated the environmental concentrations of a selection of 93 pharmaceuticals in 43 locations in the Baltic Sea and Skagerrak. The Baltic Sea is vulnerable to anthropogenic activities due to a long turnover time and a sensitive ecosystem in the brackish water. Thirty-nine of 93 pharmaceuticals were detected in at least one sample, with concentrations ranging between 0.01 and 80 ng/L. One of the pharmaceuticals investigated, the anti-epileptic drug carbamazepine, was widespread in coastal and offshore seawaters (present in 37 of 43 samples). In order to predict concentrations of pharmaceuticals in the sub-basins of the Baltic Sea, a mass balance-based grey box model was set up and the persistent, widely used carbamazepine was selected as the model substance. The model was based on hydrological and meteorological sub-basin characteristics, removal data from smaller watersheds and wastewater treatment plants, and statistics relating to population, consumption and excretion rate of carbamazepine in humans. The grey box mo...Continue Reading

Citations

Jun 20, 2020·Environmental Toxicology and Chemistry·Ewelina KortesmäkiLeif Kronberg
Feb 23, 2019·Journal of Environmental Science and Health. Part A, Toxic/hazardous Substances & Environmental Engineering·Katharina HeyeJörg Oehlmann
Aug 3, 2019·International Journal of Environmental Research and Public Health·Henrique CabralMiguel Costa Leal
Apr 26, 2020·Environmental Science and Pollution Research International·Matilda KråkströmPatrik Eklund
Oct 21, 2020·The Science of the Total Environment·Perrine BranchetPierre Doumenq
Jan 15, 2020·Environmental Science & Technology·Laura E VossenSvante Winberg
Mar 7, 2021·The Science of the Total Environment·Dongsheng ZhengYanling Zheng
Mar 20, 2021·The Science of the Total Environment·Jesús Daniel Cardoso-VeraLeobardo Manuel Gómez-Oliván
Mar 24, 2021·Environmental Science and Pollution Research International·Kathrin FischNorbert Theobald
Nov 10, 2020·Biosensors & Bioelectronics·Patrícia RebeloCristina Delerue-Matos
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Jul 20, 2021·Environmental Science and Pollution Research International·Ekaterina ChernovaNadezhda Berezina
Jul 21, 2021·Environmental Pollution·Aobo WangAnukul Buranapratheprat
Mar 4, 2020·Environmental Science & Technology·Pablo Antonio Lara-MartínJuliane Hollender
Jan 29, 2020·Environmental Science & Technology·Johannes PohlJana Weiss
Sep 3, 2021·Chemical & Pharmaceutical Bulletin·Toshinari SuzukiTetsuji Nishimura
Feb 12, 2020·The Science of the Total Environment·Thomas Thiebault

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