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Pharmacodynamic studies on mianserin and its interaction with clonidine

European Journal of Clinical Pharmacology

Jan 1, 1981

H L ElliottJ L Reid

PMID: 7341285

Abstract

There is evidence that clonidine's hypotensive effect is reduced by the concurrent administration of tricyclic antidepressants. It has been proposed that this results from an interaction at alpha 2-receptors in the brain stem where clonidine acts as a relatively selective agonist and th...read more

Mentioned in this Paper

Mianserin 20 MG
Catecholamine [EPC]
Diastolic Blood Pressure
Secretion of Saliva
Lerivon
Malignant Neoplasm of Brain Stem
Hypotensive
Adrenergic Receptor
Drug Interactions
Pharmacodynamics
Paper Details
References
  • References25
  • Citations8
123

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Absence of an effect of mianserin on the actions of clonidine or methyldopa in hypertensive patients

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Pharmacodynamic studies on mianserin and its interaction with clonidine

European Journal of Clinical Pharmacology

Jan 1, 1981

H L ElliottJ L Reid

PMID: 7341285

DOI:

Abstract

There is evidence that clonidine's hypotensive effect is reduced by the concurrent administration of tricyclic antidepressants. It has been proposed that this results from an interaction at alpha 2-receptors in the brain stem where clonidine acts as a relatively selective agonist and th...read more

Mentioned in this Paper

Mianserin 20 MG
Catecholamine [EPC]
Diastolic Blood Pressure
Secretion of Saliva
Lerivon
Malignant Neoplasm of Brain Stem
Hypotensive
Adrenergic Receptor
Drug Interactions
Pharmacodynamics

Similar Papers Found In These Feeds

GPCRs in Blood Pressure Regulation

Blood pressure is tightly regulated by blood vessel radius, which is established by hormones and/or peptides binding to GPCRs (G-protein-coupled receptors). Discover the latest research on GPCRs in blood pressure regulation here

Adrenergic Receptors: Trafficking

Adrenergic receptor trafficking is an active physiological process where adrenergic receptors are relocated from one region of the cell to another or from one type of cell to another. Discover the latest research on adrenergic receptor trafficking here.

Related Papers

European Journal of Clinical Pharmacology

Absence of an effect of mianserin on the actions of clonidine or methyldopa in hypertensive patients

European Journal of Clinical PharmacologyJanuary 1, 1983
H L ElliottJ L Reid
British Journal of Clinical Pharmacology

Assessment of the interaction between mianserin and centrally-acting antihypertensive drugs

British Journal of Clinical PharmacologyJanuary 1, 1983
H L ElliottJ L Reid
Paper Details
References
  • References25
  • Citations8
123
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