PMID: 16512693Mar 4, 2006Paper

Pharmacoeconomics of systemic therapies for lung cancer

Treatments in Respiratory Medicine
L Bordeleau

Abstract

The purpose of this article is to review the economics of systemic therapies for the treatment of lung cancer. Lung cancer treatment is moderately expensive. The overall cost to society is significant given its high incidence. Most analyses in patients with small cell lung cancer focus on supportive care measures. The economics of chemotherapy in patients with advanced small cell lung cancer, as assessed in one study, shows alternating chemotherapy to be cost effective. Numerous economic analyses of chemotherapy in patients with non-small cell lung cancer (NSCLC) have been completed using varying methodologies in a number of countries. In patients with advanced NSCLC, third generation chemotherapy in the first-line setting can be administered within reasonable incremental cost effectiveness. Single-agent docetaxel chemotherapy in the second-line setting has also been shown to fall within a reasonable cost-effective range. Based on this review, systemic therapies for lung cancer are, for the most part, cost effective. Information on the cost-utility of systemic therapies is more limited. In a population of cancer patients with poor prognosis, the inclusion of quality indicators in the calculation of costs (i.e. cost-utility anal...Continue Reading

References

May 4, 1992·The Medical Journal of Australia·M A RosenthalJ Boyages
Aug 1, 1990·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·L JaakkimainenE Rapp
Nov 1, 1995·British Journal of Cancer·W K EvansM C Wolfson
Sep 1, 1995·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·T J SmithT Le Chevalier
Jan 1, 1993·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·V Trillet-LenoirD Tomita
Mar 17, 1993·Journal of the National Cancer Institute·G H LymanL Balducci
Jan 1, 1996·CA: a Cancer Journal for Clinicians·S L ParkerP A Wingo
Dec 1, 1996·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·W K Evans, T Le Chevalier
Sep 19, 1997·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·W K EvansC C Earle
Aug 15, 1998·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·C ChouaidB Housset
Jun 9, 1999·British Journal of Cancer·C C Earle, W K Evans
Mar 16, 2000·Lung Cancer : Journal of the International Association for the Study of Lung Cancer·J A SacristánM Minshall
May 16, 2000·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·F A ShepherdJ Berille
Aug 17, 2000·Journal of the National Cancer Institute·J M BerthelotL Bordeleau
Dec 26, 2001·Lung Cancer : Journal of the International Association for the Study of Lung Cancer·Carlos Rubio-TerrésAlfredo Moyano
Jan 11, 2002·The New England Journal of Medicine·Joan H SchillerUNKNOWN Eastern Cooperative Oncology Group
Mar 1, 2002·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Natasha B LeighlPamela J Goodwin
Jul 26, 2002·Lung Cancer : Journal of the International Association for the Study of Lung Cancer·L J BillinghamM H Cullen
Aug 21, 2002·Expert Opinion on Pharmacotherapy·Jared R AdamsCharles L Bennett
Feb 4, 2003·Annals of Oncology : Official Journal of the European Society for Medical Oncology·V C G Tjan-HeijnenUNKNOWN European Organisation for Research Treatment of Cancer-Lung Cancer Group and Health Economics Unit
Dec 31, 2003·Lung Cancer : Journal of the International Association for the Study of Lung Cancer·Joan SchillerShkun Bhalla

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Citations

Sep 4, 2010·Lung Cancer : Journal of the International Association for the Study of Lung Cancer·Giovanni GiulianiStefan Walzer
Sep 9, 2010·Lung Cancer : Journal of the International Association for the Study of Lung Cancer·Winson Y CheungSri Navaratnam
Mar 4, 2009·PharmacoEconomics·Christos ChouaidAlain Vergnenegre
Mar 11, 2006·The Journal of General Virology·Louisa S ChardGraham J Belsham
Sep 18, 2007·Annals of Oncology : Official Journal of the European Society for Medical Oncology·H MellstedtH Ludwig

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