Pharmacogenetics: the Rx perspective

Expert Review of Molecular Diagnostics
G RenegarP Manasco

Abstract

Pharmacogenetics is changing the way medicines are discovered, developed and delivered to patients. In this article, we present the 'prescription' perspective--how the results of pharmacogenetic research will help minimize the risk of costly adverse drug reactions and treatment failures, by providing predictive tools to enable healthcare providers to prescribe the right medicine for the right patient. We discuss the challenges of this research and its clinical application; its implications for drug development; evolving concepts of informed consent; related ethical, legal and social issues; changing definitions of 'genetic testing'; and the creation of an international Pharmacogenetics Working Group.

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Citations

Jan 10, 2013·European Journal of Human Genetics : EJHG·Kristin Solum SteinsbekkBerge Solberg
Apr 20, 2004·Assay and Drug Development Technologies·Solveig ErikssonAnders Alderborn
Sep 1, 2009·Expert Opinion on Medical Diagnostics·Jeffrey S Ross
Jul 12, 2005·Current Medical Research and Opinion·Ulrich Mahlknecht, Susanne Voelter-Mahlknecht
May 4, 2004·Trends in Molecular Medicine·Susanne Voelter-Mahlknecht, Ulrich Mahlknecht
Nov 19, 2003·Social Studies of Science·Adam Hedgecoe, Paul Martin
Jan 11, 2003·American Journal of Clinical Pathology·Jeffrey S Ross, Geoffrey S Ginsburg
Jun 29, 2004·Advances in Anatomic Pathology·Jeffrey S RossGabriel N Hortobagyi

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