Pharmacokinetic aspects of measurement of glomerular filtration rate in the dog: a review

Journal of Veterinary Internal Medicine
R Heiene, L Moe

Abstract

Glomerular filtration rate (GFR) is estimated by means of clearance, defined as the volume of plasma that has been cleared of a particular substance per unit time. Glomerular filtration rate may be estimated by measuring the renal clearance of a filtration marker using data from both urine and plasma or by plasma clearance using only plasma data. Several alternative pharmacokinetic models are used for the calculation of clearance using various filtration markers with slightly different pharmacokinetic properties. The purpose of this article is to discuss how the choice of marker and pharmacokinetic model may influence estimated GFR values and to elucidate commonly used methods and reported GFR values in the dog.

References

Dec 1, 1978·Journal of Pharmacokinetics and Biopharmaceutics·K YamaokaT Uno
Jan 1, 1992·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·A M Peters
Dec 1, 1991·Scandinavian Journal of Clinical and Laboratory Investigation·G StakeT Monclair
May 1, 1991·Research in Veterinary Science·M A Labato, L A Ross
Apr 1, 1991·Clinical Pharmacokinetics·W R Gillespie
Jan 1, 1991·European Journal of Nuclear Medicine·A M Peters
May 1, 1990·Scandinavian Journal of Clinical and Laboratory Investigation·E KrutzénP Nilsson-Ehle
Nov 1, 1985·Kidney International·O ShemeshB D Myers
Jan 1, 1989·Research in Experimental Medicine. Zeitschrift Für Die Gesamte Experimentelle Medizin Einschliesslich Experimenteller Chirurgie·N N Izzat, J P Rosborough
Dec 1, 1988·Scandinavian Journal of Clinical and Laboratory Investigation·S E BäckP Nilsson-Ehle
Nov 1, 1972·Scandinavian Journal of Clinical and Laboratory Investigation·J Bröchner-Mortensen
Jan 1, 1981·Investigative Radiology·T A PowersR D Bowen
Mar 1, 1983·Investigative Radiology·B OlssonE Andrew
Nov 1, 1981·The Veterinary Clinics of North America. Small Animal Practice·L D Cowgill, W L Spangler
Oct 1, 1980·Journal of Pharmacokinetics and Biopharmaceutics·S Riegelman, P Collier
Oct 1, 1981·Kidney International·J J BourgoignieA Rabinovitch
Apr 1, 1980·Journal of Pharmacokinetics and Biopharmaceutics·J S Kaka, W L Hayton
Dec 21, 1995·The New England Journal of Medicine·S Woolhandler, D U Himmelstein
Jul 1, 1995·Scandinavian Journal of Clinical and Laboratory Investigation·J O NossenK J Berg
Apr 1, 1995·European Journal of Clinical Chemistry and Clinical Biochemistry : Journal of the Forum of European Clinical Chemistry Societies·W EstelbergerH Pogglitsch
Mar 1, 1995·Research in Veterinary Science·L Moe, R Heiene
Jul 1, 1994·Kidney International·K W FlorijnP C Chang
Oct 1, 1993·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·J E RobillardP A Jose
Nov 1, 1993·Kidney International·S HellersteinB A Warady
Sep 1, 1995·Research in Veterinary Science·A GleadhillA R Michell
Aug 1, 1995·European Journal of Clinical Chemistry and Clinical Biochemistry : Journal of the Forum of European Clinical Chemistry Societies·C P SoperJ L Barron
Nov 1, 1995·Annals of Clinical Biochemistry·O SugitaN Kaneda
Mar 1, 1996·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·G SternerT Almen
Mar 1, 1996·Research in Veterinary Science·A Gleadhill, A R Michell
May 1, 1996·Kidney International·K ArakawaT Saruta
Aug 1, 1996·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·M V RoccoZ K Shihabi

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Citations

May 11, 2010·Journal of Feline Medicine and Surgery·Eva VandermeulenKathelijne Y Peremans
Jul 10, 2001·Journal of Veterinary Pharmacology and Therapeutics·S Y Gardner, M G Papich
Feb 22, 2008·Journal of Veterinary Internal Medicine·N H BexfieldA R Michell
Jun 6, 2009·Journal of Veterinary Internal Medicine·K GommerenS Daminet
Aug 28, 2009·Journal of Veterinary Internal Medicine·E RaffanJ Archer
Apr 12, 2011·Acta Veterinaria Scandinavica·Tina UllebergReidun Heiene
Sep 19, 2012·The Journal of Veterinary Medical Science·Tokiko Kushiro-BankerRobert Armstrong
Dec 1, 2011·American Journal of Veterinary Research·Natalie C FinchReidun Heiene
Oct 31, 2012·American Journal of Veterinary Research·Cécile M CollignonHervé P Lefebvre
May 3, 2008·Journal of the American Animal Hospital Association·Astrid WehnerJohannes Hirschberger
Feb 5, 2005·Xenobiotica; the Fate of Foreign Compounds in Biological Systems·A S KalgutkarA Marfat
Sep 13, 2011·Research in Veterinary Science·Miki NishidaMegumi Fujiwara
Jun 15, 2010·The Veterinary Journal·Vanessa E Von Hendy-Willson, Barrak M Pressler
Jun 1, 2005·Research in Veterinary Science·V LarouteH P Lefebvre
Aug 27, 2015·American Journal of Veterinary Research·Yui SasakiKazuhisa Furuhama
Apr 13, 2005·Clinical Techniques in Small Animal Practice·Marie E Kerl, Cristi R Cook
Jun 30, 2004·The Veterinary Clinics of North America. Small Animal Practice·George E Lees
Sep 13, 2011·Journal of Veterinary Diagnostic Investigation : Official Publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·Jens RailaBarbara Kohn
Dec 5, 2003·Veterinary Clinical Pathology·J P BraunA D J Watson
Jan 4, 2001·The Journal of Small Animal Practice·S F ForsythD U Pfeiffer
May 1, 2001·American Journal of Veterinary Research·K Miyamoto
Sep 19, 2003·American Journal of Veterinary Research·William Tod DrostPaul Y Barthez
Dec 16, 2003·American Journal of Veterinary Research·Kathleen C GondaW Emmett Braselton
Jan 25, 2006·Veterinary Radiology & Ultrasound : the Official Journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association·Christopher KunzeGeorge E Lees
Mar 24, 2006·Veterinary Radiology & Ultrasound : the Official Journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association·Isabelle Goy-ThollotPaul Y Barthez
Aug 3, 2019·Journal of Veterinary Internal Medicine·Myles McKennaRosanne Jepson
May 13, 2014·Journal of Veterinary Internal Medicine·L GhysS Daminet
Aug 25, 2019·Journal of Veterinary Internal Medicine·Paola PocarVitaliano Borromeo
Mar 26, 2003·Journal of Veterinary Medicine. A, Physiology, Pathology, Clinical Medicine·N KampaE Maripuu
Nov 13, 2020·The Journal of Veterinary Medical Science·Yuichi MiyagawaNaoyuki Takemura

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