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Pharmacokinetics and safety of a raltegravir-containing regimen in HIV-infected children aged 2-12 years on rifampicin for tuberculosis

AIDS

Nov 15, 2019

Tammy M MeyersIMPAACT P1101 Team

PMID: 31689263

DOI: 10.1097/qad.0000000000002369

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Abstract

Drug-drug interactions limit current antiretroviral treatment options for HIV-infected children with tuberculosis (TB). Rifampicin (RIF) induces UDP-glucuronosyltransferase activity, accelerating the clearance of raltegravir (RAL). We sought to establish an optimal and well tolerated do...read more

Mentioned in this Paper

Hepatitis
HIV Infections
Rifampin
Treatment Protocols
Tuberculosis
Glucuronosyltransferase
Pharmacokinetic Study
Site
Coinfection
Human immunodeficiency virus 1 RNA
4
4
1
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Pharmacokinetics and safety of a raltegravir-containing regimen in HIV-infected children aged 2-12 years on rifampicin for tuberculosis

AIDS

Nov 15, 2019

Tammy M MeyersIMPAACT P1101 Team

PMID: 31689263

DOI: 10.1097/qad.0000000000002369

Abstract

Drug-drug interactions limit current antiretroviral treatment options for HIV-infected children with tuberculosis (TB). Rifampicin (RIF) induces UDP-glucuronosyltransferase activity, accelerating the clearance of raltegravir (RAL). We sought to establish an optimal and well tolerated do...read more

Mentioned in this Paper

Hepatitis
HIV Infections
Rifampin
Treatment Protocols
Tuberculosis
4
4
1

Similar Papers Found In These Feeds

Related Papers

Paper Details
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  • Citations
  • finger pointing at paper

    References currently unavailable

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