Pharmacologic and Nonpharmacologic Management of Atrial Fibrillation

The Medical Clinics of North America
Vishal Dahya, Tyler L Taigen

Abstract

Atrial fibrillation (AF) is the most common arrhythmia and its management may be organized into risk stratification and/or treatment of heart failure, stroke prevention, and symptom control. At the core of symptom control, treatment is tailored to either allow AF continue with controlled heart rates, so-called rate control, versus restoring and maintaining sinus rhythm or rhythm control. Rate control strategies mainly use rate-modulating medications, whereas rhythm control treatment includes therapy aimed at restoring sinus rhythm, including pharmacologic and direct current cardioversion, as well as maintenance of sinus rhythm, including antiarrhythmic medications and ablation therapy.

References

Feb 20, 1997·The New England Journal of Medicine·UNKNOWN Digitalis Investigation Group
Sep 3, 1998·The New England Journal of Medicine·M HaïssaguerreJ Clémenty
May 11, 2001·The New England Journal of Medicine·A L KleinUNKNOWN Assessment of Cardioversion Using Transesophageal Echocardiography Investigators
Dec 6, 2002·The New England Journal of Medicine·D G WyseUNKNOWN Atrial Fibrillation Follow-up Investigation of Rhythm Management (AFFIRM) Investigators
Dec 6, 2002·The New England Journal of Medicine·Isabelle C Van GelderUNKNOWN Rate Control versus Electrical Cardioversion for Persistent Atrial Fibrillation Study Group
Oct 15, 2003·The American Journal of Cardiology·Edward L C PritchettUNKNOWN Rythmol Atrial Fibrillation Trial (RAFT) Investigators
Jun 9, 2004·Journal of Cardiac Surgery·Niv Ad, James L Cox
Dec 3, 2004·The New England Journal of Medicine·Paolo AlboniGermano Gaggioli
May 6, 2005·The New England Journal of Medicine·Bramah N SinghUNKNOWN Sotalol Amiodarone Atrial Fibrillation Efficacy Trial (SAFE-T) Investigators
May 3, 2006·The American Journal of Medicine·Graham ThrallGregory Y H Lip
Sep 7, 2007·The New England Journal of Medicine·Bramah N SinghUNKNOWN EURIDIS and ADONIS Investigators
Jun 21, 2008·The New England Journal of Medicine·Lars KøberUNKNOWN Dronedarone Study Group
Jan 28, 2010·JAMA : the Journal of the American Medical Association·David J WilberUNKNOWN ThermoCool AF Trial Investigators
Feb 18, 2010·Heart Rhythm : the Official Journal of the Heart Rhythm Society·Maya GuglinAnne B Curtis
Mar 17, 2010·The New England Journal of Medicine·Isabelle C Van GelderUNKNOWN RACE II Investigators
Nov 16, 2011·The New England Journal of Medicine·Stuart J ConnollyUNKNOWN PALLAS Investigators
Oct 16, 2012·Heart Rhythm : the Official Journal of the Heart Rhythm Society·Anil K GehiAndy C Kiser
Oct 26, 2012·The New England Journal of Medicine·Jens Cosedis NielsenPeter Steen Hansen
Mar 19, 2013·Journal of the American College of Cardiology·Douglas L PackerUNKNOWN STOP AF Cryoablation Investigators
May 6, 2015·European Heart Journal·Mate VamosStefan H Hohnloser
Mar 13, 2016·Heart Failure Clinics·Dilesh Patel, Emile G Daoud
Aug 28, 2016·European Heart Journal·Paulus KirchhofUNKNOWN ESC Scientific Document Group
Oct 11, 2017·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Hugh CalkinsUNKNOWN Document Reviewers:
Feb 1, 2018·The New England Journal of Medicine·Nassir F MarroucheUNKNOWN CASTLE-AF Investigators
May 15, 2018·American Heart Journal·Douglas L PackerUNKNOWN CABANA Investigators

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