Pharmacologic Considerations of Anesthetic Agents in Pediatric Patients: A Comprehensive Review

Anesthesiology Clinics
Alan D KayeShilpadevi Patil

Abstract

Acute pain in the pediatric population has important differences in terms of biology, intrapopulation variation, and epidemiology. Discussion as to the pharmacologic considerations of anesthetic agents, such as induction agents, neuromuscular blockers, opioids, local anesthetics, and adjuvant agents, is presented in this article. Special considerations and concerns, such as risk for propofol infusion syndrome and adverse potential side effects of anesthesia agents, are discussed. Anesthesiologists managing pediatric patients need to have a firm understanding of physiologic and pharmacologic differences compared with the adult population. Future studies to improve the understanding of pharmacokinetics in the pediatric population are needed.

Associated Clinical Trials

Citations

Jan 24, 2020·Annals of Plastic Surgery·Jiwon Sarah CrowleySamuel Lance
Apr 9, 2020·The Journal of Pediatric Pharmacology and Therapeutics : JPPT : the Official Journal of PPAG·Rachel S MeyersDavid S Hoff
Oct 20, 2020·Arhiv za higijenu rada i toksikologiju·Sandra Alavuk KundovićKsenija Črnjar

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