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Pharmacologic disruption of TRPV1-expressing primary sensory neurons but not genetic deletion of TRPV1 protects mice against pancreatitis

Pancreas

Apr 26, 2008

Joelle M-J RomacRodger A Liddle

Abstract

Transient receptor potential subtype vanilloid 1 (TRPV1) is an ion channel that is primarily expressed by primary sensory neurons where it mediates pain and heat sensation and participates in neurogenic inflammation. In this study, we examined the role of TRPV1 during neurogenic activat...read more

Mentioned in this Paper

Nervousness
Biochemical Pathway
Systemic Inflammatory Response Syndrome
Endocytosis
Acute Pancreatitis
Pancreatitis
Neurons
Gene Deletion Abnormality
Weighing Patient
Gene Deletion
1
18
Paper Details
References
  • References32
  • Citations15
1234
  • References32
  • Citations15
12

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Pharmacologic disruption of TRPV1-expressing primary sensory neurons but not genetic deletion of TRPV1 protects mice against pancreatitis

Pancreas

Apr 26, 2008

Joelle M-J RomacRodger A Liddle

PMID: 18437086

DOI: 10.1097/mpa.0b013e318160222a

Abstract

Transient receptor potential subtype vanilloid 1 (TRPV1) is an ion channel that is primarily expressed by primary sensory neurons where it mediates pain and heat sensation and participates in neurogenic inflammation. In this study, we examined the role of TRPV1 during neurogenic activat...read more

Mentioned in this Paper

Nervousness
Biochemical Pathway
Systemic Inflammatory Response Syndrome
Endocytosis
Acute Pancreatitis
Pancreatitis
Neurons
Gene Deletion Abnormality
Weighing Patient
Gene Deletion
1
18

Similar Papers Found In These Feeds

Neuronal Cell Types

There are diverse ranges of neurons, which are defined by their structural, functional, connectional and molecular properties. For example, some type of neurons includes sensory, sympathetic, and motor neurons. Discover the latest research on neuronal cell types here.

Exocytosis & Endocytosis: Imaging

Dynamin GTPases are proteins that are responsible for endocytosis in cells, as well as division of organelles, cytokinesis, and pathogen resistance. Discover the latest research on dynamin GTPases here.

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Biochimica Et Biophysica Acta

The role of Transient Receptor Potential Vanilloid 1 (TRPV1) channels in pancreatitis

Biochimica Et Biophysica ActaApril 13, 2007
Rodger A Liddle
Paper Details
References
  • References32
  • Citations15
1234
  • References32
  • Citations15
12
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