Pharmacologic therapy for inflammatory bowel disease refractory to steroids

Clinical and Experimental Gastroenterology
M P Martínez-MontielG Castellano-Tortajada

Abstract

Although corticosteroids are an effective treatment for induction of remission in inflammatory bowel disease (IBD), many patients are dependent on or refractory to corticosteroids. This review is based on scrutinizing current literature with emphasis on randomized controlled trials, meta-analyses, and Cochrane reviews on the management of IBD refractory to corticosteroids. Based on this evidence, we propose algorithms and optimization strategies for use of immunomodulator and biologic therapy in IBD refractory to corticosteroids.

Citations

Mar 12, 2019·Inflammatory Bowel Diseases·Rhiannon T FilipponeKulmira Nurgali
Oct 2, 2019·Frontiers in Immunology·Stamatia PapoutsopoulouChris S Probert
Jul 5, 2019·Indian Journal of Gastroenterology : Official Journal of the Indian Society of Gastroenterology·Chase MeyerMatt Vassar
Apr 28, 2020·BMJ Open Gastroenterology·Ignacio Marin-JimenezManuel Barreiro-de Acosta
Jul 17, 2021·Biomedical Microdevices·Zarmeena AbidStephan S Keller
Jul 11, 2021·Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver·G BastidaM Barreiro-de Acosta

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Methods Mentioned

BETA
imaging techniques
biopsy

Software Mentioned

GEMINI
ENCORE

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