Pharmacologic therapy of mycotic keratitis

Survey of Ophthalmology
Pranita SahayNamrata Sharma

Abstract

Mycotic keratitis continues to be an important cause of corneal blindness, especially in tropical and subtropical countries. The prognosis is poor compared with many other forms of keratitis because of the lack of effective antifungal drugs. The currently available antifungal drugs suffer from multiple drawbacks such as poor ocular penetration, unpredictable bioavailability, and adverse effects associated with systemic medications. Over the last decade, several new drugs and drug-delivery systems have been introduced in an attempt to improve the treatment outcomes. Thorough knowledge of the currently available antifungal drugs, their spectrum of action, and associated adverse effects is essential to deal with cases of mycotic keratitis. We discuss the pharmacologic properties and clinical use of the currently available antifungal drugs.

Citations

Jul 28, 2019·International Journal of Molecular Sciences·Ming-Tse KuoHuey-Ling You
Dec 25, 2019·Current Eye Research·Pranita SahayJeewan S Titiyal
Oct 24, 2020·Journal of Fungi·Valeri SáenzAdriana Marcela Celis Ramírez
May 14, 2021·American Journal of Ophthalmology Case Reports·Anita RaghavanRam Rammohan
Sep 2, 2020·Current Pharmaceutical Biotechnology·Tang QinHongda Zhu

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Antifungals (ASM)

An antifungal, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis, cryptococcal meningitis, and others. Discover the latest research on antifungals here.

Antifungals

An antifungal, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis, cryptococcal meningitis, and others. Discover the latest research on antifungals here.

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