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Pharmacological characterisation of the presynaptic alpha-adrenoceptor in the rat vas deferens

European Journal of Pharmacology

Mar 21, 1977

G M Drew

Abstract

The interactions between alpha-adrenoceptor agonists and antagonists on the twitch response of the rat isolated vas deferens to low frequency motor nerve stimulatioh have been examined. Oxymetazoline, clonidine, naphazoline and BAY-1470 caused a concentration-dependent inhibition of the...read more

Mentioned in this Paper

Adrenergic alpha-Agonists
Adrenergic alpha-Antagonists
Norepinephrine Receptors
Inotropism
Vas Deferens Structure
Isoglaucon
Alpha-adrenergic receptor
In Vitro [Publication Type]
Metazoa
Electric Stimulation Technique
Paper Details
References
  • References15
  • Citations76
12
  • References15
  • Citations76
12345...

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Pharmacological characterisation of the presynaptic alpha-adrenoceptor in the rat vas deferens

European Journal of Pharmacology

Mar 21, 1977

G M Drew

PMID: 14838

DOI: 10.1016/0014-2999(77)90351-x

Abstract

The interactions between alpha-adrenoceptor agonists and antagonists on the twitch response of the rat isolated vas deferens to low frequency motor nerve stimulatioh have been examined. Oxymetazoline, clonidine, naphazoline and BAY-1470 caused a concentration-dependent inhibition of the...read more

Mentioned in this Paper

Adrenergic alpha-Agonists
Adrenergic alpha-Antagonists
Norepinephrine Receptors
Inotropism
Vas Deferens Structure
Isoglaucon
Alpha-adrenergic receptor
In Vitro [Publication Type]
Metazoa
Electric Stimulation Technique

Similar Papers Found In These Feeds

Inotropic Agents & Heart Disease

Inotropic agents alter the force or energy of muscular contractions. Negatively inotropic agents weaken the force of muscular contractions. Positively inotropic agents increase the strength of muscular contraction. Inotropic agents are used in hospitalized patients with acute decompensated heart failure, with reduced left ventricular ejection fraction and with signs of end-organ dysfunction in the setting of a low cardiac output, or with severe systolic heart failure awaiting heart transplant to maintain hemodynamic stability or as a bridge to decision. Discover the latest research on inotrpic agents and heart diseases here.

Neuromodulation

Neuromodulation refers to a physiological process in which a neuron uses chemical(s) to regulate a variety of neuronal populations. Discover the latest research on neuromodulation here.

Related Papers

British Journal of Pharmacology

Selectivity of blocking agents for pre-and postsynaptic alpha-adrenoceptors

British Journal of PharmacologyMay 1, 1977
J C DoxeyJ M Walker
Paper Details
References
  • References15
  • Citations76
12
  • References15
  • Citations76
12345...
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