Pharmacological interventions for pain in children and adolescents with life-limiting conditions

The Cochrane Database of Systematic Reviews
Emma BeechamLouise Jones

Abstract

Pain is one of the most common symptoms in children and young people (CYP) with life-limiting conditions (LLCs) which include a wide range of diagnoses including cancer. The current literature indicates that pain is not well managed, however the evidence base to guide clinicians is limited. There is a clear need for evidence from a systematic review to inform prescribing. To evaluate the evidence on the effectiveness of different pharmacological interventions used for pain in CYP with LLCs. The following electronic databases were searched up to December 2014: CENTRAL (in the Cochrane Library), MEDLINE, EMBASE, PsycINFO and CINAHL. In addition, we searched conference proceedings and reference lists of included studies. For completeness, we also contacted experts in the field. No language restrictions were applied. Randomised controlled trials (RCTs), quasi-randomised studies and other studies that included a clearly defined comparator group were included. The studies investigated pharmacological treatments for pain associated with LLCs in CYP. The treatment included those specifically developed to treat pain and those that acted as an adjuvant, where the treatment was not primarily developed to treat pain but has pain relieving ...Continue Reading

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Citations

Aug 25, 2017·Journal of Applied Research in Intellectual Disabilities : JARID·Jacqueline K DucHelen S Heussler
Sep 16, 2015·Archives of Disease in Childhood·Julia DowningRichard Harding

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