Pharmacological manipulation of memory reconsolidation: towards a novel treatment of pathogenic memories

European Journal of Pharmacology
Leontien DiergaardeTaco J De Vries

Abstract

Well-consolidated memories, when retrieved, may return to a transiently fragile state, and need to be consolidated again in order to be maintained. This process has been referred to as memory reconsolidation and presumably serves to modify or strengthen memory traces. In recent years, our understanding of the neurobiological mechanisms underlying this phenomenon has increased rapidly. Here, we will briefly review some of the pharmacological evidence, stressing a crucial role for the brain's major neurotransmitter systems, such as glutamate and noradrenaline, in memory reconsolidation. Pharmacological intervention of reconsolidation processes may have clinical relevance, especially for the treatment of psychiatric disorders that are characterized by pathological memories, including post-traumatic stress disorder and addictive behaviour.

References

Mar 1, 1997·Behavioural Brain Research·J Przybyslawski, S J Sara
Aug 17, 2002·Trends in Neurosciences·James L McGaugh
Nov 1, 2002·Neuron·Maria H Milekic, Cristina M Alberini
Oct 3, 2003·Neurobiology of Learning and Memory·Ann E PowerJames L McGaugh
Dec 9, 2003·Progress in Neuro-psychopharmacology & Biological Psychiatry·Benno Roozendaal
Apr 9, 2004·Proceedings of the National Academy of Sciences of the United States of America·K Matthew Lattal, Ted Abel
May 21, 2004·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Akinobu SuzukiSatoshi Kida
Jul 16, 2004·Learning & Memory·Sophie TronelSusan J Sara
Oct 22, 2004·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Sevil Duvarci, Karim Nader
Jan 14, 2005·Learning & Memory·Meritxell Torras-GarciaSusan J Sara
Apr 1, 2005·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Jennifer N Gelinas, Peter V Nguyen
Apr 19, 2005·Proceedings of the National Academy of Sciences of the United States of America·Jeffrey W DalleyTrevor W Robbins
Sep 17, 2005·Learning & Memory·Federico Bermudez-RattoniJames L McGaugh
Oct 6, 2005·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Yi-Ling YangKwok-Tung Lu
Mar 17, 2006·Neurobiology of Learning and Memory·Roberto A Prado-AlcaláJames L McGaugh
Mar 18, 2006·Neuroscience·S G BustosV A Molina
Apr 8, 2006·Behavioural Brain Research·Leontien DiergaardeTaco J De Vries
Aug 26, 2006·Neuroreport·Rick E BernardiStephen P Berger
Sep 15, 2006·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Wen-Hui CaiCraig M Powell
Sep 26, 2006·Nature Neuroscience·Cyrinne Ben MamouKarim Nader
Sep 29, 2006·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Jonathan L C LeeBarry J Everitt
Oct 5, 2006·Psychopharmacology·Mohini Ranganathan, Deepak Cyril D'Souza
Nov 10, 2006·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Jacqueline K Rose, Catharine H Rankin
Mar 8, 2007·Nature Reviews. Neuroscience·Natalie C Tronson, Jane R Taylor
May 1, 2007·The European Journal of Neuroscience·Benedetto SacchettiPiergiorgio Strata
May 2, 2007·Neuroreport·Jonathan B KelleyYossef Itzhak
Jun 8, 2007·The European Journal of Neuroscience·Tali KobiloYadin Dudai
Jun 15, 2007·Neurobiology of Learning and Memory·Luciana A IzquierdoIvan Izquierdo

❮ Previous
Next ❯

Citations

Sep 29, 2011·Psychopharmacology·Yu OhmuraMitsuhiro Yoshioka
Jun 25, 2013·Behavioural Brain Research·Marina A GrudenVladimir V Sherstnev
May 15, 2013·European Journal of Pharmacology·Ana M ValentimLuís M Antunes
Aug 14, 2009·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Daisuke YamadaMasayuki Sekiguchi
Feb 5, 2009·Nature Reviews. Neuroscience·Susan J Sara
Jun 3, 2010·Learning & Memory·Elizaveta V Muravieva, Cristina M Alberini
Jun 23, 2010·Proceedings of the National Academy of Sciences of the United States of America·Stephen M TaubenfeldCristina M Alberini
Dec 11, 2013·Neurobiology of Learning and Memory·Michael B VanElzakkerLisa M Shin
Jul 21, 2014·Nicotine & Tobacco Research : Official Journal of the Society for Research on Nicotine and Tobacco·Alessia AuberCristiano Chiamulera
Jun 4, 2014·Current Psychiatry Reports·Eric VermettenHarm J Krugers
Sep 26, 2014·Expert Opinion on Drug Discovery·Chris P Bailey, Stephen M Husbands
Aug 19, 2015·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Moritz J W SchrammAmy L Milton
Aug 11, 2012·Progress in Neurobiology·Antoine BesnardSerge Laroche
May 28, 2013·Journal of Pharmacological Sciences·Yu OhmuraMitsuhiro Yoshioka
Sep 11, 2016·Brain Research·Pasha Ghazal
Jan 24, 2019·Addiction Biology·Christina DinterFalk Kiefer
Sep 18, 2014·Behavioural Pharmacology·Vincenzo TedescoCristiano Chiamulera
Jun 5, 2019·The European Journal of Neuroscience·Horst SchicknickWolfgang Tischmeyer
Nov 13, 2017·Behavioural Brain Research·Kyle Z PasquarielloPaul J Meyer
Jul 3, 2021·International Journal of Molecular Sciences·Einat ElharrarGal Yadid
Apr 15, 2009·Current Opinion in Psychiatry
Dec 18, 2013·Learning & Memory·Cristina A J SternLeandro J Bertoglio
Dec 20, 2013·Learning & Memory·Marcelo E PiñeyroGonzalo P Urcelay

❮ Previous
Next ❯

Related Concepts

Related Feeds

Addiction

This feed focuses mechanisms underlying addiction and addictive behaviour including heroin and opium dependence, alcohol intoxication, gambling, and tobacco addiction.

Amygdala: Sensory Processes

Amygdalae, nuclei clusters located in the temporal lobe of the brain, play a role in memory, emotional responses, and decision-making. Here is the latest research on sensory processes in the amygdala.

Basal Forebrain- Circuits

Basal forebrain is a region in the brain important for production of acetylcholine and is the major cholinergic output of the CNS. Discover the latest research on circuits in the basal forebrain here.

Anxiety Disorders

Discover the latest research on anxiety disorders including agoraphobia, panic disorder, obsessive-compulsive disorder, and post-traumatic stress disorder here.

Adrenergic Receptors: Trafficking

Adrenergic receptor trafficking is an active physiological process where adrenergic receptors are relocated from one region of the cell to another or from one type of cell to another. Discover the latest research on adrenergic receptor trafficking here.

Amygdala and Midbrain Dopamine

The midbrain dopamine system is widely studied for its involvement in emotional and motivational behavior. Some of these neurons receive information from the amygdala and project throughout the cortex. When the circuit and transmission of dopamine is disrupted symptoms may present. Here is the latest research on the amygdala and midbrain dopamine.

© 2022 Meta ULC. All rights reserved