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Pharmacological modulation of brain activity in a preclinical model of osteoarthritis

NeuroImage

Sep 18, 2012

Jaymin UpadhyayM Day

Abstract

The earliest stages of osteoarthritis are characterized by peripheral pathology; however, during disease progression chronic pain emerges-a major symptom of osteoarthritis linked to neuroplasticity. Recent clinical imaging studies involving chronic pain patients, including osteoarthriti...read more

Mentioned in this Paper

Neuro-Oncological Ventral Antigen 2
Imaging Studies
Mucocutaneous Lymph Node Syndrome
Biochemical Pathway
Pyrazoles
Salicylhydroxamic acid
Entire Brainstem
Tomography, Emission-Computed, Single-Photon
Visual Analog Pain Scale
Auriculotemporal Syndrome
Paper Details
References
  • References65
  • Citations10
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  • References65
  • Citations10
1

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Pharmacological modulation of brain activity in a preclinical model of osteoarthritis

NeuroImage

Sep 18, 2012

Jaymin UpadhyayM Day

PMID: 22982372

DOI: 10.1016/j.neuroimage.2012.08.084

Abstract

The earliest stages of osteoarthritis are characterized by peripheral pathology; however, during disease progression chronic pain emerges-a major symptom of osteoarthritis linked to neuroplasticity. Recent clinical imaging studies involving chronic pain patients, including osteoarthriti...read more

Mentioned in this Paper

Neuro-Oncological Ventral Antigen 2
Imaging Studies
Mucocutaneous Lymph Node Syndrome
Biochemical Pathway
Pyrazoles
Salicylhydroxamic acid
Entire Brainstem
Tomography, Emission-Computed, Single-Photon
Visual Analog Pain Scale
Auriculotemporal Syndrome

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Functional MRI

Functional magnetic resonance imaging (fMRI) images blood flow in the brain, using it as proxy for brain activity. It can also be used to look for brain abnormalities. To stay up to date on fMRI research, follow this feed.

Limbic System

The limbic system is comprised of several different parts of the brain involved in emotion, motivation, learning, and memory. Discover the latest research on the limbic system here.

Related Papers

Current Rheumatology Reports

Role of functional brain imaging in understanding rheumatic pain

Current Rheumatology ReportsSeptember 1, 2012
Anthony K P JonesAlison Watson
Paper Details
References
  • References65
  • Citations10
12345...
  • References65
  • Citations10
1
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