Pharmacologically-induced stress has minimal impact on judgement and attention biases in sheep

Scientific Reports
Jessica E MonkCaroline Lee

Abstract

The emotional impact of exposure to stressors has not been well quantified in animals. We hypothesised that exogenous induction of stress in sheep would induce a pessimistic judgement bias and increased attention towards a threatening stimulus, suggestive of a negative emotional state. Stress was induced pharmacologically by administering synthetic adrenocorticotropic hormone. Judgement bias was assessed using a spatial go/no-go task after exposure to acute stress (one injection), chronic stress (21 daily injections) and acute-on-chronic stress (2 min isolation after 28 daily injections). Attention bias was assessed during chronic stress only (22 daily injections). In contrast with our hypotheses, there was no strong evidence that Synacthen administration altered judgement bias or attention bias at any stage of the experiment. Stressed sheep were more likely to approach ambiguous locations than saline Control animals, however, statistical evidence for models fitting treatment group was very weak. Overall, our findings suggest that elevated levels of cortisol may not fully explain changes to judgement bias observed in previous studies after environmentally-induced stress. Further studies are required to better understand which a...Continue Reading

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Citations

Aug 6, 2020·Animals : an Open Access Journal From MDPI·Jessica E MonkDana L M Campbell
Oct 22, 2020·Scientific Reports·Sarah L HobbsRowena M A Packer
Aug 28, 2021·Animals : an Open Access Journal From MDPI·Mallory G AndersonLeonie Jacobs
Aug 30, 2021·Neuroscience and Biobehavioral Reviews·Benjamin LecorpsMarina A G von Keyserlingk
Nov 28, 2021·Scientific Reports·Louise KremerCornelis G van Reenen

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